Publications by authors named "Mina Stephanos"
Article Synopsis
- * Findings show that low CVP significantly reduces intraoperative blood loss but does not affect blood transfusion needs, mean arterial pressure, or operative time.
- * The authors suggest that while low CVP may be beneficial, more extensive randomized controlled trials are needed for stronger evidence regarding its overall impact on surgical outcomes.
Objectives: To assess whether intraperitoneal contamination index (ICI) (Hajibandeh index) derived from combined levels of CRP, lactate, neutrophils, lymphocytes, and albumin can predict the nature of intraperitoneal contamination in patients with acute abdominal pathology and to assess whether ICI can predict postoperative mortality in patients undergoing emergency laparotomy.
Methods: In order to prospectively validate the ICI, developed and validated retrospectively in our previous study, a multicentre prospective cohort study was conducted between January 2019 and June 2020 including all adult patients who presented with acute abdominal pathology requiring emergency laparotomy. ROC curve analysis was performed to determine discrimination and cut-off values of preoperative ICI that could predict the nature of intraperitoneal contamination and postoperative mortality.