Evaluation of glutathione peroxidase in the blood and tumor tissue of oral squamous cell carcinoma patients.

Aims And Objectives: The lowered antioxidant capacity and the oxidant-antioxidant imbalance have been considered to play a role in multistage carcinogenesis. The deleterious effects produced by reactive oxygen species depend on the imbalance between oxidant and antioxidant status in the body, so this study is aimed to evaluate the levels of antioxidant enzyme, glutathione peroxidase (GPx), in the blood and tumor tissues of oral squamous cell carcinoma (OSCC) patients in comparison with healthy controls.

Materials And Methods: The study comprised of 38 participants divided into two groups.