Publications by authors named "Min-jie Liao"
Article Synopsis
- The study investigated the prevalence of human papillomavirus (HPV) and its impact on prognosis in patients with vaginal cancer (VC) over a 31-year period.
- Out of 79 VC patients, 98.6% of squamous cell carcinoma (SCC) and 83.3% of non-SCC cases tested positive for HPV, with HPV16 being the most common type.
- Key findings revealed that advanced stages (III/IV) and lymph node metastasis were linked to worse survival rates, while positivity for p16 and HPV was associated with a better prognosis.
Stress-induced phosphoprotein-1 (STIP1)-a heat shock protein (HSP)70/HSP90 adaptor protein-is commonly overexpressed in malignant cells, where it controls proliferation via multiple signaling pathways, including JAK2/STAT3. We have previously shown that STIP1 stabilizes the protein tyrosine kinase JAK2 in cancer cells via HSP90 binding. In this study, we demonstrate that STIP1 may act as a substrate for JAK2 and that phosphorylation of tyrosine residues 134 and 152 promoted STIP1 protein stability, induced its nuclear-cytoplasmic shuttling, and promoted its secretion into the extracellular space.
View Article and Find Full Text PDFHuman papillomavirus (HPV) is the well-established etiologic factor for cervical neoplasia. Cervical conization constitutes an effective treatment for high-grade cervical intraepithelial neoplasia (HG-CIN). We conducted an observational study for long-term outcomes and HPV genotype changes after conization for HG-CIN.
View Article and Find Full Text PDFObjective: To observe the effects of Chinese herb of promoting blood circulation to dissipate blood stasis on the levels of tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) in serum of patients with mudslide injuries, and investigate the mechanisms of Chinese herb of promoting blood circulation to dissipate blood stasis in the treatment of mudslide injuries.
Methods: Patients with mudslide injuries who were translated from Zhouqu and Chengxian to Lanzhou from 12th August 2010 were divided into two groups (group A and group B). Twenty-five patients in group A, containing 15 males and 10 females, with an average age of (39.