A comprehensive multi-tiered approach to assessing weather penalties on O levels and exceedance days in Seoul using generalized additive models (2001-2019).

Over the past two decades, ambient O air pollution in Seoul, the capital city of South Korea, has increased. As a secondary air pollutant, O is affected not only by precursor gas emissions but also by meteorological conditions. This study examined the influence of weather changes in Seoul for 2001-2019 on the long-term daily maximum 8-h O concentration (MDA8 O) trends measured at 25 monitoring sites.

Capabilities of satellite Geostationary Environment Monitoring Spectrometer (GEMS) NO data for hourly ambient NO exposure modeling.

The Geostationary Environment Monitoring Spectrometer (GEMS) is the world's first geostationary instrument that monitors hourly gaseous air pollutant levels, including nitrogen dioxide (NO). Using the first-of-its-kind capabilities of GEMS NO data, we examined how well GEMS NO levels can explain the spatiotemporal variabilities in hourly NO concentrations in the Republic of Korea for the year 2022. A correlation analysis between hourly GEMS NO levels and ground NO concentrations showed a higher spatial correlation [Pearson r = 0.

Association of rheumatoid arthritis and high sodium intake with major adverse cardiovascular events: a cross-sectional study from the seventh Korean National Health and Nutrition Examination Survey.

Objectives: High salt intake has a harmful effect on hypertension; however, the association between major adverse cardiovascular events (MACE) and salt intake is still controversial. Rheumatoid arthritis (RA) is also characterised by excess cardiovascular risk. However, few studies have investigated the combined role of salt intake and RA in MACE in the general Korean population.

Development and Validation of a Risk Scoring Model for Early Prediction of Severe Colon Ischemia.

Background: Colon ischemia (CI) is injury to the intestines secondary to insufficient blood flow. Its clinical severity can range from mild to life-threatening.

Aims: To investigate predictive risk factors for CI and propose a scoring model for severe outcomes.

Three-dimensional motion capture data during repetitive overarm throwing practice.

Three-dimensional motion capture analysis is considered the gold standard for any movement research. Motion capture data were recorded for 7 healthy female participants with no prior throwing experience to investigate the learning process for overarm throwing during a selected period. Participants were monitored 3 times a week for 5 weeks.

Fibroblast Growth Factor 10 Enhances the Developmental Efficiency of Somatic Cell Nuclear Transfer Embryos by Accelerating the Kinetics of Cleavage During In Vitro Maturation.

Somatic cell nuclear transfer (SCNT) is required for the generation of transgenic animals as disease models. During the in vitro development of SCNT embryos, the quality of matured oocytes is one of the major factors regulating the developmental potential of embryos. Time-lapse monitoring systems are new tools that assess the developmental capacity of embryos for use in embryo transfer.

Production of transgenic pig as an Alzheimer's disease model using a multi-cistronic vector system.

Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with memory loss and cognitive impairments. An AD transgenic (Tg) pig model would be useful for preclinical testing of therapeutic agents. We generated an AD Tg pig by somatic cell nuclear transfer (SCNT) using a multi-cistronic vector that harbored three AD-related genes with a total of six well-characterized mutations: hAPP (K670N/M671L, I716V, and V717I), hTau (P301L), and hPS1 (M146V and L286P).

Association between Growth Differentiation Factor 15 (GDF15) and Cardiovascular Risk in Patients with Newly Diagnosed Type 2 Diabetes Mellitus.

We investigated an association between serum Growth Differentiation Factor 15 (GDF15) level and cardiovascular risk in patients with newly diagnosed type 2 diabetes mellitus (T2D). A total of 107 participants were screened for T2D and divided into a T2D group and a control group (without diabetes). We used the Framingham risk score (FRS) and the New Pooled Cohort Equation score to estimate the 10-year risk of atherosclerotic cardiovascular disease.

Effects of Feeder Cell Types on Culture of Mouse Embryonic Stem Cell In Vitro.

The suitable feeder cell layer is important for culture of embryonic stem (ES) cells. In this study, we investigated the effect of two kinds of the feeder cell, MEF cells and STO cells, layer to mouse ES (mES) cell culture for maintenance of stemness. We compare the colony formations, alkaline phosphatase (AP) activities, expression of pluripotency marker genes and proteins of D3 cell colonies cultured on MEF feeder cell layer (D3/MEF) or STO cell layers (D3/STO) compared to feeder free condition (D3/-) as a control group.

A case of low bone mineral density with vitamin d deficiency due to prolonged lactation and severe malnutrition.

Malnutrition associated vitamin D deficiency contributes to the calcium loss from bone and results in osteoporosis and osteomalacia at final stage. Osteomalacia is characterized with softening of bone secondary to defective bone mineralization. Here, we report a case of possible osteomalacia caused by prolonged lactation and severe malnutrition in 35-year-old female.