Publications by authors named "Min-Soo Jang"

Article Synopsis
  • The study examined the effects of wearing masks during the COVID-19 pandemic on facial skin issues, known as facial dermatoses, through a nationwide survey in Korea.
  • Results showed that 75.9% of patients experienced worsening or new facial skin conditions linked to prolonged mask-wearing, with specific trends noted among different skin issues.
  • Factors such as gender, age, and duration of mask use influenced the severity and type of facial dermatoses, highlighting the varied clinical features based on the specific condition.
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Background: More than half of acne patients have truncal acne on their chest, back, and shoulders. However, since most studies on acne have focused on the face, data on clinical characteristics and proper management for truncal acne are insufficient.

Objective: To establish a Korean Acne Rosacea Society (KARS) consensus for experts' perception and treatment patterns of truncal acne.

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This was a cross-sectional study conducted to evaluate the association between hearing impairment and low back pain (LBP) using data from the Korean National Health and Nutrition Examination Survey. A total of 5,504 middle-aged and older Korean adults (aged ≥50 years old) who underwent plain radiography of the lumbar spine and pure tone audiometry were included. The presence of LBP was evaluated using a questionnaire, which included a question on whether the patient had experienced LBP that lasted for more than 30 days during the past three months.

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Background/purpose: The pathogenesis of chronic actinic dermatitis (CAD) is more complicated than other photodermatoses. However, the relationship between the clinical severity of CAD and the offending photocontact or contact allergens or both, and the correlations of CAD immunopathogenesis with the immunoregulatory molecules involved in adaptive immunity are yet to be investigated.

Methods: We performed phototesting with broad-spectrum ultraviolet (UV) B, UVA, and visible light to establish the presence of photosensitivity in 121 patients with CAD, together with photopatch and contact patch testing.

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Patients with chronic itch describe their pruritus in a wide variety of ways. However, these subjective descriptions are often not taken into consideration by physicians. This study aimed to validate patients' descriptions of pruritus, and to investigate the relationship between various descriptions of pruritus and the patient burden of chronic pruritus by examining the mediating effects of sleep disturbance and sexual dysfunction on patient's quality of life, as predicted by various descriptions of pruritus.

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Since large cell acanthoma (LCA) has many overlapping clinical and histopathological features with other epidermal pigmented tumours, an additional method to differentiate it would be of great clinical significance. A retrospective study was performed on 33 lesions (26 patients) to identify distinct dermoscopic findings of LCA and to describe dermoscopic-histopathological correlations. The results revealed that dermoscopy significantly aids in the distinction of LCA from other epidermal tumours included in the differential diagnosis.

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Article Synopsis
  • The study investigates three types of genital keratotic lesions: bowenoid papulosis (BP), which is linked to high-risk HPV; condyloma acuminatum (CA), associated with low-risk HPV; and genital seborrheic keratosis (GSK), a benign tumor without a clear HPV connection.
  • Findings show that both BP and GSK are related to high-risk HPV, while CA is tied to low-risk HPV, suggesting that GSK may be a distinct tumor rather than just an aging form of CA.
  • The presence of high-risk HPV in GSK raises concerns for physicians, emphasizing the need for more proactive treatment and ongoing monitoring of these patients.
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Article Synopsis
  • Dermatologists face challenges in diagnosing keratotic or warty lesions in the genital area due to overlapping features of conditions like bowenoid papulosis, seborrheic keratosis, and condyloma acuminatum.
  • The study compared dermoscopic features of these lesions, finding that bowenoid papulosis showed predominant glomerular vessels and mucosal pigmentation, while seborrheic keratosis was less vascular and had a cerebriform appearance.
  • Condyloma acuminatum was identified by its finger-like shape and highly vascular features, with distinct findings that can aid in non-invasive differentiation of these lesions.
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Background: Data regarding Asian patients with mycosis fungoides (MF) are limited.

Objective: We aimed to investigate the clinical profile and long-term outcomes of patients with MF in Korea.

Methods: A retrospective review of 223 patients with MF who were followed up for more than 6 months or died of MF within 6 months of diagnosis was performed.

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Spark's nevus is a compound word composed of Spitz nevus and Clark's nevus. It is one of the combined melanocytic nevi which is more common in female and usually presents as a sharp circumscribed hyperpigmented macule on the lower extremities. On histopathologic findings, both cytologic features of Spitz nevus characterized as large spindle or epithelioid melanocytes containing large nuclei with abundant cytoplasm, and architecture of Clark's nevus characterized as elongation of rete ridges, bridging of the nests, concentric and lamellar fibrosis can be seen.

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Background/purpose: Atopic dermatitis (AD) is an inflammatory skin disease characterized by a chronic course of exacerbations and remissions. High-dose ultraviolet A-1 (UVA-1) phototherapy has been effective in the treatment of acute exacerbations of AD. However, there have been no case studies in Asian patients to date.

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Article Synopsis
  • Low-dose methotrexate (MTX) is commonly used for various skin diseases but is not officially recommended for solitary or localized primary cutaneous anaplastic large cell lymphoma (PCALCL) in treatment guidelines.
  • A study analyzed long-term outcomes of 7 Asian patients with solitary or localized PCALCL treated with low-dose MTX, revealing that 85.7% achieved complete response and 14.3% had partial remission.
  • Despite some patients experiencing relapses during an average follow-up of 92.1 months, all participants remained alive without disease, suggesting MTX is an effective and safe option for treating this condition.
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Background: Several tools can provide a reliable and accurate evaluation of pruritus, including the visual analog scale (VAS), numeric rating scale (NRS), verbal rating scale (VRS), and multidimensional questionnaires such as the Itch Severity Scale (ISS). However, no single method is considered a gold standard.

Objective: We evaluated the validity and reliability of VAS, NRS, VRS, and ISS and their correlation with a pruritus-specific quality of life instrument, ItchyQoL.

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Background: Psoriasis and psoriatic arthritis (PsA) are included in the group of immune-mediated inflammatory diseases (IMIDs) caused by systemic inflammation; however, indicators for monitoring inflammatory activity in patients with psoriasis, such as the Psoriasis Area and Severity Index (PASI), are limited.

Objective: To determine whether the Psoriatic Arthritis Screening and Evaluation (PASE) questionnaire can be used to monitor disease activity in patients with psoriasis.

Methods: This was a multicenter, noninterventional, cross-sectional study.

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Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disorder. Although several epidemiological studies have been conducted in Western countries, such data regarding Asian populations are scarce. In this study, we sought to investigate the demographic and clinical features of HS in Korea.

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Background: Increased photoprotection by natural melanin allows for African-Americans to be less impacted by photoaging than Caucasians. However, less is known about chronological aging in this population.

Objective: To create a photonumeric scale for African-Americans to evaluate chronological skin aging and to explore contributing elements to intrinsic aging.

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