Publications by authors named "Min-Hua Shen"
Egg yolk immunoglobulin (IgY) and LL37, potent antibacterial substances, can fight against periodontitis. This work aimed to develop a locally injectable hydrogel for potential co-delivery of special IgY and LL37-loaded solid lipid nanoparticles (LL37-SLNs) to synergistically inhibit the proliferation of oral pathogens, thus relieving periodontal inflammation and redness. The formulation of thermosensitive hydrogel loaded with IgY and LL37-SLNs was developed by adopting the Quality by Design approach.
View Article and Find Full Text PDF[Effect of platelet rich fibrin combining with Bio-oss to treat furcation involvement].
Shanghai Kou Qiang Yi Xue
October 2018
Purpose: To evaluate the effect of platelet rich fibrin (PRF) combining with Bio-oss in treating Class II furcation involvement.
Methods: Thirty patients who had Class Ⅱ furcation involvement in the mandibular first molar were included. They were all free of systemic disease.
[Effect of photodynamic therapy on IL-1beta and MMP-8 in gingival crevicular fluid of chronic periodontitis].
Shanghai Kou Qiang Yi Xue
February 2008
Purpose: Photodynamic therapy (PDT) is used in infectious disease for its antimicrobial effects. The aim of the study is to evaluate the effects of a diode laser-based photodynamic therapy on the treatment of chronic periodontitis.
Methods: Fifty eight patients with chronic periodontitis were divided into three groups.
[Detection and significance of IL-1beta and MMP-8 in patients with periodontitis of whole unstimulated saliva].
Shanghai Kou Qiang Yi Xue
April 2007
Article Synopsis
- The study aimed to investigate the presence of IL-1beta and MMP-8 in the saliva of patients with different types of periodontitis and explore their potential as biomarkers for the disease.
- Researchers collected saliva samples from 80 individuals, including patients with generalized chronic periodontitis (GCP), generalized aggressive periodontitis (GAgP), and healthy controls, measuring levels of IL-1beta and MMP-8.
- Results showed no significant difference in IL-1beta levels across the groups, but MMP-8 levels were significantly higher in both periodontitis groups compared to controls, suggesting MMP-8 could serve as a potential biomarker while more research on IL-1beta is needed.