Effect of finishing condition on fracture strength of monolithic zirconia crowns.

This study was to evaluate the load bearing capacity of monolithic dental zirconia crowns, and the effect of surface finishing on fracture strength. (1) The zirconia plates were divided into 5 groups and polished by various types of polishing bur, every specimen was analyzed by surface roughness testing, and X-ray diffraction (XRD). (2) The zirconia crowns were classified into 4 groups corresponding to different surface treatments and thickness.

Endoscopic Endonasal Versus Transorbital Surgery for Middle Cranial Fossa Tumors: Comparison of Clinical Outcomes Based on Surgical Corridors.

Background: Based on our experience with the endoscopic endonasal approach (EEA) and transorbital approach (TOA) for middle cranial fossa tumors, we evaluated the efficacy and limitations of visualization and the clinical outcomes associated with the approaches depending on the surgical corridors. In addition, we determined the optimal strategy for each approach.

Methods: Between September 2015 and May 2018, we retrospectively reviewed clinical outcomes in 21 patients who underwent minimally invasive endoscopic surgery for middle cranial fossa tumors involving the cavernous sinus.

Which Factors Affect the Rate of Surgery Performed in Patients with Carpal Tunnel Syndrome?

Background: Carpal tunnel release is recommended when patients have positive electrophysiologic test and their symptoms are not resolved in spite of conservative treatment. However, only some of them eventually undergo the surgery. The purposes of this study, therefore, were to evaluate the rate of carpal tunnel release performed among the patients with positive electrophysiologic test, and to identify which factors were associated with the rate of the surgery.

The influence of histology on the response of brain metastases to gamma knife radiosurgery: a propensity score-matched study.

Background: In terms of response to fractionated radiotherapy, metastatic brain tumors of certain origins are considered radioresistant.

Objective: To determine the influence of "radioresistant" histology on outcomes of brain metastases treated with radiosurgery.

Methods: Between 2001 and 2017, 121 patients with brain metastases from renal cell carcinoma (RCC) and 2151 from non-small cell lung cancer (NSCLC) were reviewed.

Left Ventricular Ejection Fraction Predicts Poststroke Cardiovascular Events and Mortality in Patients without Atrial Fibrillation and Coronary Heart Disease.

Background And Objectives: It is controversial that decreased left ventricular function could predict poststroke outcomes. The purpose of this study is to elucidate whether left ventricular ejection fraction (LVEF) can predict cardiovascular events and mortality in acute ischemic stroke (AIS) without atrial fibrillation (AF) and coronary heart disease (CHD).

Methods: Transthoracic echocardiography was conducted consecutively in patients with AIS or transient ischemic attack at Soonchunhyang University Hospital between January 2008 and July 2016.

Transradial versus transfemoral intervention in non-ST-segment elevation acute coronary syndrome patients undergoing percutaneous coronary intervention: the Korean transradial intervention registry of 1 285 patients.

Introduction: Although the implementation of transradial intervention (TRI) has increased over the last few years, there are limited data on the impact of TRI on efficacy and safety in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). We sought to compare one-year clinical outcomes and bleeding complications of TRI with those of transfemoral intervention (TFI) in patients with NSTE-ACS.

Methods: The Korean TRI registry was a cohort of 20 centres from 2012 to 2015.

Enhancement of bone formation on LBL-coated Mg alloy depending on the different concentration of BMP-2.

To control the bio-absorption rate of Mg alloy and improve its biocompatibility, a BMP-2 of various concentrations (20, 50, and 100 ng/mL) was immobilized in the carrier layer formed by micro-arc oxidation + hydrothermal treatment on the surface of Mg alloy. Their morphological and chemical properties were evaluated by FE-SEM with EDS and XRD. The electrochemical corrosion behavior was examined, and the cytotoxicity was assessed by WST and ALP assay.

Chitosan-gold nanoparticles mediated gene delivery of c-myb facilitates osseointegration of dental implants in ovariectomized rat.

Osseointegration of dental implants is affected by osteoporosis. The purpose of this study was overcome the implant failure and facilitate the osseointegration of dental implants by c-myb in ovariectomized (OVX)-induced osteoporosis. c-myb is a transcription factor and supports bone formation.

The effect of short-term preoperative ureteral stenting on the outcomes of retrograde intrarenal surgery for renal stones.

Objectives: To evaluate the effect of preoperative ureteral stenting duration on the outcomes of retrograde intrarenal surgery (RIRS).

Patients And Methods: We reviewed our database of patients who underwent RIRS between May 2011 and April 2017 at our institution. The patients were divided into three groups according to preoperative ureteral stenting duration: group 1: no stenting, group 2: short preoperative stenting (< 7 days) and group 3: long preoperative stenting (≥ 7 days).

Anti-inflammatory effects of Kaempferol on Helicobacter pylori-induced inflammation.

Inflammation induced by Helicobacter pylori infection related to gastric carcinogenesis. In this study, we have investigated the anti-inflammatory effect and its mechanism of kaempferol in the inflammatory response caused by H. pylori infection in vitro.

Improvement of osteogenesis by a uniform PCL coating on a magnesium screw for biodegradable applications.

A polymer coating as polycaprolactone (PCL) is applied to improve the initial corrosion resistance of biodegradable magnesium. In addition, plasma electrolytic oxidation (PEO) is performed to increase adhesion between the polymer and the metal. However, when a complex-shaped material such as a screw is implanted in a bone, the surface coatings are locally damaged, and the protective role of the coating is not sufficiently maintained.

Membrane-Based Microwave-Mediated Electrochemical Immunoassay for the In Vitro, Highly Sensitive Detection of Osteoporosis-Related Biomarkers.

Highly sensitive and multiplexed in vitro detection of osteoporosis-related biochemical markers were carried out based on the membrane-based microwave-mediated electrochemical immunoassay (MMeEIA), where we can dramatically reduce the sample preparation time by shortening the incubation time of conjugation to obtain sensitive detection based on three dimensional conjugation of antibodies with target antigens in nylon membrane disk. C-terminal cross-linked telopeptide of type I collagen (CTx), Osteocalcin (OC), parathyroid hormone (PTH), and N-terminal propeptide of type I collagen (P1NP), which can be utilized to monitor the progress of osteoporosis, were quantified using their corresponding antibody immobilized in membranes. Coefficient of variations in this intra- and inter-assays were within 8.

and Characterization of N-Acetyl-L-Cysteine Loaded Beta-Tricalcium Phosphate Scaffolds.

Beta-tricalcium phosphate bioceramics are widely used as bone replacement scaffolds in bone tissue engineering. The purpose of this study is to develop beta-tricalcium phosphate scaffold with the optimum mechanical properties and porosity and to identify the effect of N-acetyl-L-cysteine loaded to beta-tricalcium phosphate scaffold on the enhancement of biocompatibility. The various interconnected porous scaffolds were fabricated using slurries containing various concentrations of beta-tricalcium phosphate and different coating times by replica method using polyurethane foam as a passing material.

Mental fatigue in central-field and peripheral-field steady-state visually evoked potential and its effects on event-related potential responses.

The steady-state visually evoked potential (SSVEP) is a natural response of the brain to visual stimulation at specific frequencies and is used widely for electroencephalography-based brain-computer interface (BCI) systems. Although the SSVEP is useful for its high level of decoding accuracy, visual fatigue from the repetitive visual flickering is an unavoidable problem. In addition, hybrid BCI systems that combine the SSVEP with the event-related potential (ERP) have been proposed recently.

Author Correction: Plasmonic Chromatic Electrode with Low Resistivity.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

A High Performance Spelling System based on EEG-EOG Signals With Visual Feedback.

In this paper, we propose a highly accurate and fast spelling system that employs multi-modal electroencephalography-electrooculography (EEG-EOG) signals and visual feedback technology. Over the last 20 years, various types of speller systems have been developed in brain-computer interface and EOG/eye-tracking research; however, these conventional systems have a tradeoff between the spelling accuracy (or decoding) and typing speed. Healthy users and physically challenged participants, in particular, may become exhausted quickly; thus, there is a need for a speller system with fast typing speed while retaining a high level of spelling accuracy.

Sucrose challenges to Streptococcus mutans biofilms and the curve fitting for the biofilm changes.

The relationship between sugar level and development of dental caries has long been a main topic in dentistry. However, as a ubiquitous component of the modern diet, sucrose is mainly derived from three meals a day, rather than a long time exposure. In this study, various concentrations of sucrose were provided to Streptococcus mutans biofilms for 1 h per exposure (three times per day) to imitate a human meal pattern.

Gas formation and biological effects of biodegradable magnesium in a preclinical and clinical observation.

Magnesium alloys are biodegradable metals receiving increasing attention, but the clinical applications of these materials are delayed by concerns over the rapid corrosion rate and gas formation. Unlike corrosion, which weakens mechanical properties, the gas formation issue has received little attention. Therefore, we evaluated the gas formation and biological effects for Mg implants through preclinical (immersed in Earle's balanced salt solution and ) and clinical studies.

Label-Free Impedance Sensing of Aflatoxin B₁ with Polyaniline Nanofibers/Au Nanoparticle Electrode Array.

Aflatoxin B (AFB₁) is produced by the and group of fungi which is most hepatotoxic and hepatocarcinogenic and occurs as a contaminant in a variety of foods. AFB₁ is mutagenic, teratogenic, and causes immunosuppression in animals and is mostly found in peanuts, corn, and food grains. Therefore, novel methodologies of sensitive and expedient strategy are often required to detect mycotoxins at the lowest level.

Phelligridin D-loaded oral nanotube titanium implant enhances osseointegration and prevents osteolysis in rat mandible.

Poor bone quality and osteolysis are the major causes of implant failure in dentistry. Here, this study tested the effect of phelligridin D-loaded nanotubes titanium (Ti) for bone formation around the dental implants. The purpose of this study was to enhance osseointegration of phelligridin D-loaded implant into the bone for bone formation and prevention of osteolysis.

Electrochemical immunosensor for highly sensitive and quantitative detection of tumor necrosis factor-α in human serum.

Highly sensitive and selective biosensors for accurate determination of specific protein biomarkers at low levels in serum are a prerequisite for the present healthcare systems. Therefore, here we developed a label-free impedimetric method for tumor necrosis factor-alpha (TNF-α) detection using reduced graphene oxide (RGO) with gold nanoparticles (AuNP) on an indium tin oxide (ITO) microdisk electrodes. The detection mechanism relies on resistance change occurs due to [Fe(CN)] redox probe movement towards the conductive channels of the AuNP-RGO films gated by the recognition of the target biomarker by its anti-TNF-α antibody.

Short stature is associated with the development of lower limb ischaemia during extracorporeal life support.

Background: Percutaneous cannulation of femoral vessels has been widely used for the rapid deployment of extracorporeal life support (ECLS). Limb ischaemia is a devastating complication in patients receiving ECLS. Our aim was to evaluate the predictors of limb ischaemia during ECLS and to determine the role of preventative distal perfusion.

Spliceosome-Associated Protein 130 Exacerbates Alcohol-Induced Liver Injury by Inducing NLRP3 Inflammasome-Mediated IL-1β in Mice.

Excessive alcohol consumption leads to chronic liver diseases. Macrophage-inducible C-type lectin (Mincle) is a C-type lectin receptor that recognizes spliceosome-associated protein 130 (SAP130) known as an endogenous ligand released from dying cells. The aim was to examine the role of Mincle-SAP130 in the pathogenesis of alcoholic liver disease.

Effect of Lithium Disilicate Reinforced Liner Treatment on Bond and Fracture Strengths of Bilayered Zirconia All-Ceramic Crown.

This study was performed to evaluate the effect of a lithium-disilicate spray-liner application on both the bond strength between zirconia cores and heat-pressed lithium-disilicate glass-ceramic veneers, and the fracture strength of all-ceramic zirconia crowns. A lithium-disilicate reinforced liner was applied on the surface of a zirconia core and lithium-disilicate glass-ceramic was veneered on zirconia through heat press forming. Microtensile and crown fracture tests were conducted in order to evaluate, respectively, the bonding strength between the zirconia cores and heat pressed lithium-disilicate glass-ceramic veneers, and the fracture strength of bilayered zirconia all-ceramic crowns.