Publications by authors named "Min W Lee"

The rapid evolution of microelectronics and display technologies has driven the demand for advanced manufacturing techniques capable of precise, high-speed microchip transfer. As devices shrink in size and increase in complexity, scalable and contactless methods for microscale placement are essential. Laser-induced forward transfer (LIFT) has emerged as a transformative solution, offering the precision and adaptability required for next-generation applications such as micro-light-emitting diodes (μ-LEDs).

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In the rapidly evolving healthcare environment, radiologists strive to establish their rightful place. Thus, there is a need for enhanced outpatient and clinical education within the Department of Radiology and exploration of its methodologies. Accordingly, the Korean Society of Radiology established a task force to investigate the clinical and outpatient practice status of radiologists overseas, current state of related education, involvement of other specialties in radiologic practices and education in Korea, and clinical and outpatient practice status among Korean radiologists.

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Background: Radiofrequency ablation (RFA) of subphrenic hepatocellular carcinomas (HCCs) using ultrasound (US) guidance presents a challenge.

Purpose: To evaluate local tumor progression (LTP) and overall survival (OS) after RFA of right posterior subphrenic HCCs, and to identify the risk factors for LTP and OS after RFA.

Material And Methods: We screened patients who underwent US-guided RFA for a single HCC <3 cm in the right posterior subphrenic area.

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Article Synopsis
  • * Analyzed data from 86 patients showed that multiple LN metrics were linked to overall survival (OS), disease-free survival (DFS), and distant metastasis-free survival (DMFS), particularly highlighting the number of metastatic LNs (LNN) as a strong predictor in multivariable analysis.
  • * Key findings included LNN ≥ 2 as a significant factor for OS, DFS, and DMFS, while lymph node ratio (LNR) was notable for DFS and DMFS; however, certain parameters like log odds of positive
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Background And Aims: Liver transplantation (LT) is a curative treatment for end-stage liver disease. Anastomotic biliary strictures (ABS) are more common in living donor LT (LDLT). However, the success rate of endoscopic retrograde cholangiopancreatography (ERCP) for ABS remains unsatisfactory.

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Two Gram-stain-negative, strictly aerobic, non-motile, rod-shaped bacteria, designated as strains S88 and W115, exhibiting catalase- and oxidase-positive reactions, were isolated from marine red algae in South Korea. Strain S88 exhibited growth at 20-30 °C, pH 6.0-9.

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  • The study focused on creating a machine learning model to predict pulmonary embolism (PE) in patients with gastrointestinal cancers, who are at a higher risk for this condition.
  • Researchers analyzed data from 585 patients who had undergone computed tomographic pulmonary angiography (CTPA) across two hospitals, using factors like the Wells score and D-dimer levels to train the model.
  • The model demonstrated effectiveness by achieving an area under the receiver operating curve (AUROC) of 0.736 in one hospital and 0.669 in another, showing that it could significantly reduce unnecessary CTPA referrals compared to traditional diagnostic methods.
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  • The study focused on identifying factors that predict late intrahepatic recurrence (IHR) of hepatocellular carcinoma (HCC) occurring over two years after curative treatment.
  • It involved analysis of 2,304 patients who received curative treatment and were monitored for more than two years, revealing that 35.4% experienced late IHR.
  • Key prognostic factors for late IHR included age, male sex, cirrhosis at diagnosis, type of treatment, and modified albumin-bilirubin (mALBI) grade measured at three and six months post-treatment.
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  • Researchers created membranes using a combination of porous silicon dioxide (SiO) and poly(vinylidene fluoride) (PVdF) through a process called electrospinning.
  • The composite membranes have tunable thickness and low thermal shrinkage, demonstrating stability at high temperatures but showing changes in electrical properties at around 170°C to 225°C.
  • Even after exposure to temperatures over 270°C, the membranes maintained their structure without collapsing, indicating good thermal resilience.
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Local ablation therapy, encompassing radiofrequency ablation (RFA), microwave ablation, and cryoablation, has emerged as a crucial strategy for managing small hepatocellular carcinomas (HCCs), complementing liver resection and transplantation. This review delves into the clinical significance of tumor size, location, and biology in guiding treatment decisions for HCCs undergoing local ablation therapy, with a focus on tumors smaller than 3 cm. Tumor size significantly influences treatment outcomes, with larger tumors associated with poorer local tumor control due to challenges in creating sufficient ablative margins and the likelihood of microvascular invasion and peritumoral satellite nodules.

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Objective: We analyzed the incidence and mortality rate of gastrointestinal (GI) tract perforation after radiofrequency ablation (RFA) for hepatic tumors and assess its risk factors.

Methods: This retrospective cohort study included 4799 patients with malignant tumors who underwent RFA (n = 7206). Sixty-nine cases of thermal injury to the GI tract were identified via a search of the electronic medical record system using index terms and divided into two groups according to the thermal injury with (n = 8) or without (n = 61) GI tract perforation based on follow-up CT reports.

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  • The study aimed to assess the effectiveness of contrast-enhanced ultrasonography (CEUS) using Sonazoid for identifying focal liver lesions (FLLs) that appeared uncertain on traditional MRI scans in patients not at risk for liver cancer.
  • Researchers analyzed data from 97 patients, comparing the diagnostic accuracy of MRI alone versus MRI combined with CEUS, finding a slight increase in performance but no significant statistical difference.
  • While CEUS didn't markedly enhance overall diagnostic accuracy for these indeterminate lesions, it showed potential in boosting radiologists' confidence in making evaluations.
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Background: Intratumoral heterogeneity (ITH) and tumor microenvironment (TME) of pancreatic ductal adenocarcinoma (PDAC) play important roles in tumor evolution and patient outcomes. However, the precise characterization of diverse cell populations and their crosstalk associated with PDAC progression and metastasis is still challenging.

Methods: We performed single-cell RNA sequencing (scRNA-seq) of treatment-naïve primary PDAC samples with and without paired liver metastasis samples to understand the interplay between ITH and TME in the PDAC evolution and its clinical associations.

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Background/aim: This study aimed to compare the oncological outcomes of proton beam radiotherapy (PBT) with those of radiofrequency ablation (RFA) for newly diagnosed hepatocellular carcinoma (HCC).

Patients And Methods: This study included 323 patients who underwent PBT (n=40) or RFA (n=283) as a curative treatment for previously untreated HCC between October 2016 and June 2021. The primary endpoints were local progression and toxicity.

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  • The study evaluates how well GPT-4 can extract liver cancer-related information (LI-RADS features) from MRI reports written in both Korean and English.
  • Researchers created 160 fake reports and considered both these and genuine reports to test the model's accuracy in extracting the relevant data.
  • Results showed high accuracy (up to 99% for some features), but the model still needs improvements for consistency and effectiveness in real-world applications.
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Background And Aims: It is difficult to differentiate between neoplastic and non-neoplastic gallbladder (GB) polyps before surgery. EUS-guided elastography (EUS-EG) is a noninvasive complementary diagnostic method. The utility of EUS-EG in the differential diagnosis of GB polyps has not been investigated.

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Previous studies have reported the association between myocardial infarction (MI) and air pollution (AP). However, limited information is available regarding the long-term effects of AP on the relative incidence rates of ST-elevation MI (STEMI) and Non-ST-elevation MI (NSTEMI). We investigated the association between long-term exposure to AP and the incidence of STEMI.

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Two Gram-stain-negative, strictly aerobic rods, designated as RMAR6-6 and KMA01, exhibiting catalase- and oxidase-positive activities, were isolated from marine red algae in the Republic of Korea. Cells of strain RMAR6-6 exhibited flagellar motility, while those of strain KMA01 were non-motile. Strain RMAR6-6 exhibited optimal growth at 30-35°C and pH 7.

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Purpose: This study aimed to evaluate the long-term clinical outcomes based on the ligation level of the inferior mesenteric artery (IMA) in patients with rectal cancer.

Methods: This was a retrospective analysis of a prospectively collected database that included all patients who underwent elective low anterior resection for rectal cancer between January 2013 and December 2019. The clinical outcomes included oncological outcomes, postoperative complications, and functional outcomes.

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Objective: To investigate superb microvascular imaging (SMI), a novel Doppler ultrasound technique that can visualize low-velocity microvascular flow, for assessing pediatric focal nodular hyperplasia (FNH).

Patients And Methods: Nine FNH lesions in 6 patients were enrolled. On SMI and color Doppler imaging (CDI), intralesional vascularity was assessed visually and categorized as typical spoke-wheel pattern (central vessel radiating from the center to the periphery), multifocal spoke-wheel pattern, and nonspecific pattern.

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Purpose: To investigate cases of vitreous opacity (VO) similar to asteroid hyalosis (AH) after intravitreal brolucizumab injection.

Methods: A retrospective chart review was conducted to identify cases showing VO similar to AH among patients who received intravitreal brolucizumab injections at our retinal clinic from January 2022 to January 2023.

Results: A total of 220 brolucizumab injections were administered at our hospital.

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Background: Sarcopenia or visceral adipose tissue has been reported to be related to pancreatic cancer prognosis. However, clinical relevance of the comprehensive analysis of body compositions and their longitudinal changes is lacking. This study analysed the association between body composition changes after chemotherapy and survival in patients with metastatic pancreatic cancer.

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Background/aims: The aim of this study was to examine whether the efficacy of radiofrequency ablation (RFA) and surgical resection (SR) are comparable for hepatocellular carcinoma (HCC) less than 3 cm in elderly individuals aged 65 years or older.

Methods: We used the National Health Insurance Service claims data in Korea, which was linked with liver cancer stage data from the Central Cancer Registry of the National Cancer Center, as well as death data from the National Statistical Office. Out of the 9213 registrants, we focused on 141 patients who underwent SR and 225 patients who underwent RFA when they were 65 years or older.

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Although the disease burden of elderly cancer patients is rapidly increasing, reliable scientific information, value and preference information of domestic patients, and standardized guidelines for determining the treatment of elderly cancer patients are lacking. The aim of this study is to compare the therapeutic effects of radiofrequency ablation (RFA) and surgery in hepatocellular carcinoma (HCC) patients aged 65 years or older. For the meta-analysis, the databases including PubMed (MEDLINE), EMBASE, OVID Medline, and the Cochrane Library were systematically searched.

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Article Synopsis
  • * The study found that piceamycin suppresses key genes involved in tumor growth and metastasis while also disrupting cell invasion and migration.
  • * A combination of piceamycin and gemcitabine enhances their effectiveness, suggesting a potential new strategy for combating resistance in pancreatic cancer treatment.
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