Publications by authors named "Min Jia Zhu"
[Effects of Aging on Endothelium-dependent Vasodilation of Human Artery].
Sichuan Da Xue Xue Bao Yi Xue Ban
March 2019
Article Synopsis
- The study aimed to investigate how aging affects the ability of human arteries to dilate, focusing on the gastroepiploic artery from patients with stomach cancer aged 51 to 83.
- Results showed that both types of vasodilation—endothelium-dependent and induced by endothelial-derived hyperpolarizing factor (EDHF)—decreased with age, alongside a reduction in relevant mRNA expressions related to nitric oxide and other signaling molecules.
- The conclusion suggests that aging negatively impacts the function of vasodilation in arteries, likely due to lower levels of nitric oxide, hydrogen sulfide, and C-type natriuretic peptide.
Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics.
Pharmacogenet Genomics
August 2009
Background: 5'-Nucleotidases play a critical role in nucleotide pool balance and in the metabolism of nucleoside analogs such as gemcitabine and cytosine arabinoside (AraC). We previously performed an expression array association study with gemcitabine and AraC cytotoxicity using 197 human lymphoblastoid cell lines. One gene that was significantly associated with gemcitabine cytotoxicity was a nucleotidase family member, NT5C3.
View Article and Find Full Text PDF[Progress in the study of ATP-binding cassette transporter A1].
Sheng Li Ke Xue Jin Zhan
October 2005