Publications by authors named "Mimouni M"
Purpose: To compare outcomes between patients treated with a single cyanoacrylate tissue adhesive (CTA) patch for corneal thinning or perforation and those requiring multiple CTA applications.
Methods: We conducted a single-center, comparative cohort study of patients with corneal thinning or perforation treated with either a single or multiple CTA applications in Toronto, Canada, between 2006 and 2024. Primary outcomes were the need for penetrating keratoplasty (PKP) and the best-corrected visual acuity (BCVA) at final follow-up.
Purpose: To examine the safety and efficacy of combined treatment with topical ivermectin 1% and intense pulsed light (IPL) for dry eye disease (DED) secondary to demodex blepharitis.
Methods: A retrospective review of medical files of patients treated at a private clinic specializing in DED between November 2022 and February 2024 was performed. Sixty-one patients aged 18 years or older with DED because of demodex blepharitis, who received the IPL and ivermectin 1% combination therapy, were included.
Article Synopsis
- The study aimed to assess the effectiveness of subconjunctival tranexamic acid (TXA) in reducing bleeding, shortening surgery time, and enhancing recovery in pterygium surgery through a double-blind, randomized controlled trial involving 50 patients.
- Results showed no significant differences between the TXA group and the saline control group in terms of surgery duration, intraoperative bleeding, or postoperative visual acuity, with both groups faring similarly in all main outcome measures.
- Although the use of TXA was deemed safe with no adverse effects, the findings suggest that it does not provide substantial benefits in improving surgical outcomes for pterygium surgery, indicating a need for further research on alternative treatments or surgical techniques.
Reasons for Re-treatment Following Monovision Laser Refractive Surgery.
J Refract Surg
November 2024
Purpose: To assess the incidence and causes for re-treatment following monovision laser refractive surgery in a large data study spanning a decade.
Methods: The setting for this retrospective comparative study was Care Vision Laser Center, Tel Aviv, Israel. This study included patients aged 36 to 60 years who underwent monovision laser vision correction at the Care Vision Laser Centers, Israel, from January 2012 to December 2022.
Purpose: To identify factors predicting slow visual recovery following myopic microkeratome assisted in situ keratomileusis (LASIK).
Design: Retrospective study.
Methods: This study included consecutive patients who underwent microkeratome-assisted myopic LASIK between January 2005 and December 2019 at Care Vision Laser Center, Tel Aviv, Israel.
Purpose: To identify factors predicting slow visual recovery following photorefractive keratectomy (PRK).
Methods: This retrospective study included consecutive patients who underwent PRK between January 2005 and December 2019 at Care Vision Laser Center, Tel Aviv, Israel. Myopic patients were divided into 2 groups according to whether they experienced normal recovery of visual acuity (within 60 days) or slow visual recovery (>60 days).
Article Synopsis
- The study aimed to compare LASIK surgery outcomes among patients with varying corneal curvatures (flat, normal, and steep).
- A total of 300 eyes from each curvature group were analyzed after matching for baseline characteristics, with primary outcomes including visual acuity and astigmatism.
- Results showed no significant differences in postoperative effectiveness or safety between the groups, indicating that LASIK is equally safe and effective regardless of corneal curvature.
Gemini AI vs. ChatGPT: A comprehensive examination alongside ophthalmology residents in medical knowledge.
Graefes Arch Clin Exp Ophthalmol
February 2025
Introduction: The rapid advancement of artificial intelligence (AI), particularly in large language models like ChatGPT and Google's Gemini AI, marks a transformative era in technological innovation. This study explores the potential of AI in ophthalmology, focusing on the capabilities of ChatGPT and Gemini AI. While these models hold promise for medical education and clinical support, their integration requires comprehensive evaluation.
View Article and Find Full Text PDFTopic: Topical nonsteroidal anti-inflammatory drugs (NSAIDs) for management of pain in patients after photorefractive keratectomy (PRK).
Clinical Relevance: Pain after PRK is a major concern for both patients and surgeons. Although evidence supports the use of NSAIDs postoperatively, no consensus exists regarding the preferred regimen.
Article Synopsis
- AI has transformed the field of ophthalmology, particularly in diagnosing and managing corneal diseases, improving early detection and personalized treatment methods.
- Advanced imaging techniques like slit-lamp biomicroscopy and AS-OCT have integrated AI to enhance clinical decision-making and prognosis for conditions such as keratoconus and infectious keratitis.
- Despite its successes, current AI models face limitations, including binary classification that may overlook the complexities of real-world cases involving multiple coexisting conditions.
Article Synopsis
- - The study aimed to evaluate a new instrument for measuring intraocular pressure (IOP) without applying pressure to the cornea.
- - Sixteen healthy volunteers participated, and IOP was measured multiple times using both the prototype and established reference instruments, showing no significant difference overall.
- - The findings suggest that the prototype has good clinical agreement with traditional methods, but further research is needed, especially involving glaucoma patients.
Purpose: To identify potential factors associated with keratoconus.
Methods: This cross-sectional study included data from Israel's largest healthcare provider for the years 2005-2020. Keratoconus patients and age-matched controls were identified.
Background: The systematic use of susceptibility testing and tailored first-line treatment for Helicobacter pylori eradication has yet to be established.
Aim: To compare 14-day tailored PCR-guided triple therapy to 14-day non-Bismuth concomitant quadruple therapy for first-line Helicobacter pylori eradication.
Patients And Methods: We performed a multicenter, parallel-group, randomized noninferiority controlled trial.
Purpose: The aim of the study was to analyze the time-savings associated with introduction of Streamlight™ (Alcon Laboratories, Fort Worth, TX, USA) transepithelial photorefractive keratectomy (PRK) in surface corneal ablations.
Methods: All refractive surgeries were performed using the Alcon WaveLight® EX500 at the ArtLife Clinic, Gdańsk, Poland. The study included patients treated for refractive errors with transepithelial PRK between April 2019 and October 2021, who were matched with patients treated with alcohol-assisted PRK during the same period.
Background: A focused bibliographic analysis of Israel's ophthalmology research productivity has never been performed.
Objectives: To assess the research output of Israeli ophthalmology departments between the years 2011-2021 and compare to leading countries in the discipline.
Methods: The PubMed search engine was used to detect all medical articles published between the years 2011 and 2021, with at least one author from an Israeli ophthalmology department.
Purpose: To identify risk factors that increase the likelihood of re-treatment following refractive surgery in patients with mixed astigmatism.
Methods: This was a retrospective study including patients who underwent either laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK) between 2000 and 2019 and had mixed astigmatism (spherical error of +0.50 D or greater and spherical equivalent of less than 0.
Corneal allogeneic intrastromal ring segments (CAIRS) refer to the placement of allogeneic rings and segments in intrastromal channels within the cornea. Currently, a deepithelialized donor cornea is used as the allogeneic source for CAIRS and the cut ring is turned sideways and implanted so that the thickness can be varied by varying the distance between the concentric trephine blades. In addition, to obtain a greater effect, CAIRSs are preferred to be implanted with the Bowman layer (BL) facing the corneal apex and posterior stroma facing limbally.
View Article and Find Full Text PDFHyperopic LASIK and postoperative corneal steepness: revisiting the 49-diopter limit.
J Cataract Refract Surg
June 2024
Purpose: To compare corrected distance visual acuity (CDVA) outcomes of hyperopic laser in situ keratomileusis (LASIK) with a postoperative corneal steepness above vs below 49 diopters (D).
Setting: Care-Vision Laser Centers, Tel-Aviv, Israel.
Design: Retrospective study.
Recurrent herpetic keratitis is a leading cause of blindness worldwide. In this population-based cross-sectional study, the medical records of Israeli adolescents and young adults who underwent systematic preconscription evaluation for mandatory military service were reviewed. The prevalence of atopic conjunctival disease was evaluated in cases with and without documented recurrent herpetic keratitis.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to find risk factors for developing ectasia after keratorefractive surgery in patients whose scans appeared normal, introducing a new measurement tool called the diameter of peak locations (DPL).
- - Researchers analyzed data from 19 ectasia cases and 58 matched controls across multiple factors, finding that the symmetry index of the posterior cornea and the DPL were significant predictors of ectasia risk, while other factors showed no notable differences.
- - Results suggest that a higher posterior symmetry index and a tighter DPL indicate a weakened cornea, enhancing the likelihood of ectasia occurring despite previously normal tomography readings.
Fibrosis is a common feature of cardiovascular diseases and targets multiple organs, such as the heart and vessels. Endothelial to mesenchymal transition is a complex, vital process that occurs during embryonic formation and plays a crucial role in cardiac development. It is also a fundamental process implicated in cardiac fibrosis and repair, but also in other organs.
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