Evaluation of a Language and Literacy Enhancement Program.

Reading aloud to children encourages language development. Pediatricians promote reading practices through Reach Out and Read (ROR) and other methods. This exploratory study sought to examine the value that supplemental materials promoting "Touch, Talk, Read, Play" (TTRP) might provide in addition to ROR.

Lipid A structures containing novel lipid moieties: synthesis and adjuvant properties.

Structurally well-defined immune stimulatory molecules are important components of new generation molecular vaccines. In this paper, the design and synthesis of two lipid A analogues containing an unnatural tri-lipid acyl group are described. In a totally synthetic liposomal vaccine system, these re-designed lipid A analogues demonstrate potent immune stimulatory properties including antigen specific T-cell activation.