NADPH oxidase and redox status in amygdala, hippocampus and cortex of male Wistar rats in an animal model of post-traumatic stress disorder.

Post-traumatic stress disorder (PTSD) is a highly prevalent and impairing disorder. Oxidative stress is implicated in its pathogenesis. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is an important source of free radicals.

Depression in breast cancer patients.

Breast cancer is the third most common illness in the world and the most frequent malignant disease with women. Cytotoxic therapy is connected to significant psychiatric adverse effects, and the appearance of depressive symptoms is the most common. The main goal is determining the degree of depression with breast cancer patients in the oncology ward of the University Clinical Hospital in Niš and its connection to their marital status, age, level of education, economic status and the number of therapy cycles.

Long-Term Treatment with Olanzapine in Hospital Conditions: Prevalence and Predictors of the Metabolic Syndrome.

Introduction: The risk of metabolic abnormalities is greatly increased in schizophrenic patients started on an atypical antipsychotic medication. Patients with psychiatric disorders exceed mortality ranges resulting from, among others, increased risk of cardiovascular events. Other factors contributing to the development of metabolic syndrome include prolonged duration of illness, increasing age, female sex and lifestyle factors.

Metabolic syndrome and C-reactive protein in patients with depressive disorder on antidepressive medication.

Introduction: Recurrent depression is a psychiatric disorder of which etiology and pathogenesis might be related to immune response. Metabolic Syndrome (MetS) and its components are also strongly associated with elevated inflammatory indicators, as so as the body mass index (BMI) and total cholesterol levels.

Objective: Objective of this study was to investigate if there was any difference in C-reactive protein (CRP) levels in patients with recurrent depressive disorder, treated with antidepressants, compared to a healthy control group of subjects and if there was an association between increased CRP levels and the presence of MetS in these two groups.

Analysis of quality of life and anxiety in patients with different forms of epilepsy.

Background: Anxiety symptoms may have significant implications on the quality of life of patients with epilepsy. The aim of our research is a comparative analysis of the quality of life, i.e.

[Development of forensic psychiatry in Serbia].

The development of legislation in the field of mental health in our region is linked with the emergence and development of the oldest psychiatric hospitals in Serbia.The principle that the mentally ill who committed a criminal offense need to be placed in a psychiatric hospital instead of a prison was introduced at the same time as in the most developed European countries. The founders of the Serbian forensic psychiatry, Dr.

Burnout, quality of life and emotional profile in general practitioners and psychiatrists.

Objective: Many studies confirm that psychological factors and burnout in physicians are interconnected. It is however not known, whether quality of life is another factor that plays a role in this connection.The aim of this study was to explore the correlation between quality of life and emotional profile with the level of burnout in physicians.

Inhibitory role of monovalent ions on rat brain cortex adenylyl cyclase activity.

Adenylyl cyclases, comprise of a large family of enzymes that catalyze synthesis of the cyclic AMP from ATP. The aim of our study was to determine the effect of monovalent ions on both basal, stimulated adenylate cyclase EC 4.6.

[Dysfunctionality of the primary family as a supportive factor for the development of polytoxicomany in young people].

Introduction: Dependent behaviour represents a strong homeostasis of the family of an addict.

Objective: The aim of our research is to record and explore irregularities during the addicts' growth, as well as the specific type of family relations in the addicts' family.

Methods: For research purposes a general questionnaire was used on growth and development, and GRADIR questionnaire on the assessment of family relationships.

Most common diagnoses requiring physical restriction of psychiatric patients: humanity at the test.

Introduction: Attitude about physical restriction has been changing through history. It has always been multidimensional approach, including ethic, medical and judicial aspect.

Objective: The main aim was establishing distribution of physical restrictions of patients for the following years: 2006/07, 2007/08, 2008/09, 2009/10 and 2010/11.

Aggression in adolescents: characteristics and treatment.

Introduction: Vulnerability of young people and frustration of their basic biological, emotional, cognitive and social needs can induce a series of psycho-pathological manifestations, including aggression.

Objective: Aim of this study is to examine the manifestations of aggressiveness in young people and to establish the difference between aggressive responses of two age groups; adolescents aged 16-19 years and older adolescents aged 20-26 years.

Methods: The sample consists of 100 young people aged 16-19 years (46 adolescents) and 20-26 years (54 adolescents).

Hetero-aggressive outbursts in patients' behaviour in emergency psychiatry.

Introduction: Hetero-aggressive behaviour in patients with mental disorders is frequent and requires special skills of doctors and other medical staff in order to urgently protect the patient and indicate hospitalization.

Objective: The objective of this paper was to examine the frequency of the most common diagnostic categories in psychiatric patients with hetero-aggressive behaviour. The secondary objective was to examine aspects of realized hospitalization (voluntary, involuntary) and socio-demographic characteristics of these patients.

Lamotrigine augmentation in delirium tremens.

Introduction: Delirium tremens (DT) is most severe neurological complication of alcohol withdrawal with high mortality rate. DT is related to an altered balance of excitatory and inhibitory amino-acid neurotransmitters, which is basically due to upregulation of glutaminergic neurotransmission induced by chronic ethanol exposure. Lamotrigine (LTG) is believed to act by reducing excitatory glutamate release due to inhibition of Na (+) channels.

Reasons and conditions for involuntary hospitalization with special emphasis on detention without consent of mentally disordered person who voluntarily started hospital treatment.

The nature of some mental illness is such that persons affected by their conduct endangering life, health and safety, as well as life, health and safety of others from their surroundings. These persons, because of their mental condition, are often unable to properly assess their own interest. Because of the above it is permitted for these persons, under certain circumstances, to be forcibly hospitalized against their will.

Development of hospital treatment of persons with mental disorders.

Discordances of harmonic mental functioning are as old as the human kind. Psychopathological behaviour of an individual in the past was not treated as an illness. That means that psychopathology was not considered an illness.

Silicotuberculosis and silicosis as occupational diseases: report of two cases.

Introduction: Silicosis, the most prevalent of the pneumoconioses, is caused by inhalation of crystalline silica particles. Silica-exposed workers are at increased risk for tuberculosis and other mycobacterium-related diseases. The risk of a patient with silicosis developing tuberculosis is higher (2.

Anxiety in epileptic patients.

Background: Anxiety may occur as ictal, postictal or interictal symptom in patients with epilepsy. The main aim of this research was to explore the intensity and frequency of anxiety in patients with generalized, temporal and extratemporal epilepsy.

Subjects And Methods: This is a cross-sectional study of three groups of patients with epilepsy (30 patients per group) - recently diagnosed with generalized epilepsy, temporal epilepsy and extratemporal epilepsy, and a healthy control group (N=30).

Correlation of pre-morbid alcoholism and changes in the level of biogenic amine metabolites in cerebrospinal fluid of accute brain infarction patients.

Background: The disorder of biogenic amine metabolism (serotonin - 5-HT and dopamine - DA) is expected in the brain (neuron) damage caused by acute ischemia. It is known that long-term abuse of ethyl-alcohol damages the quality of neurons diffusely in the brain. Cerebrospinal fluid (CSF) and its biochemical content, 5-HT and DA, are reliable indicators of the vitality of neurons.

Development of polytoxicomania in function of defence from psychoticism.

Introduction: Polytoxicomanic proportions in subpopulations of youth have been growing steadily in recent decades, and this trend is pan-continental. Psychoticism is a psychological construct that assumes special basic dimensions of personality disintegration and cognitive functions. Psychoticism may, in general, be the basis of pathological functioning of youth and influence the patterns of thought, feelings and actions that cause dysfunction.

[Professional stress in general practitioners and psychiatrists--the level of psycologic distress and burnout risk].

Background/aim: So far, studies of stress have shown that physicians are at a high risk of sickness from psychic and somatic disorders related to professional stress, that can lead to important disturbance of personal, familiar and professional functionating. The aim of this study was to investigate the doctors exposition level to professional stress, to compare stress level in general practitioners (GP) group with that in the group of psychiatrists and risk level for the apperance of burnout syndrome.

Methods: This cross-section study included subjects recruited by a random sample method.