Publications by authors named "Milou Brandsen"
Pediatr Pulmonol
November 2024
Article Synopsis
- - The study focuses on factors influencing the decision to start biologics in children with severe asthma, as existing research is limited on this topic despite the availability of treatments.
- - Analysis was conducted on a group of 72 pediatric patients, revealing that higher GINA treatment steps, steroid toxicity, and a frequency of exacerbations were significant predictors for initiating biologic therapy.
- - The findings indicate a clinical need for biologics in children experiencing steroid toxicity, while highlighting other demographic and clinical factors that could influence treatment decisions.
J Infect Dis
December 2024
Article Synopsis
- Young children and older adults are particularly vulnerable to invasive pneumococcal disease (IPD) due to lower levels of protective antibodies against Streptococcus pneumoniae.
- Research measured IgG and IgA antibodies in serum and saliva across different age groups, revealing that younger children have significantly lower antibody levels and avidity compared to adults.
- The findings suggest that repeated exposure to pneumococci through factors like daycare attendance boosts antibody levels, with young children’s low antibody profiles contributing to their susceptibility to IPD and older adults experiencing different influencing factors.
