Automated segmentation of cell organelles in volume electron microscopy using deep learning.

Recent advances in computing power triggered the use of artificial intelligence in image analysis in life sciences. To train these algorithms, a large enough set of certified labeled data is required. The trained neural network is then capable of producing accurate instance segmentation results that will then need to be re-assembled into the original dataset: the entire process requires substantial expertise and time to achieve quantifiable results.

U-Net based vessel segmentation for murine brains with small micro-magnetic resonance imaging reference datasets.

Identification and quantitative segmentation of individual blood vessels in mice visualized with preclinical imaging techniques is a tedious, manual or semiautomated task that can require weeks of reviewing hundreds of levels of individual data sets. Preclinical imaging, such as micro-magnetic resonance imaging (μMRI) can produce tomographic datasets of murine vasculature across length scales and organs, which is of outmost importance to study tumor progression, angiogenesis, or vascular risk factors for diseases such as Alzheimer's. Training a neural network capable of accurate segmentation results requires a sufficiently large amount of labelled data, which takes a long time to compile.

In-situ PLL-g-PEG Functionalized Nanopore for Enhancing Protein Characterization.

Single-molecule nanopore detection technology has revolutionized proteomics research by enabling highly sensitive and label-free detection of individual proteins. Herein, we designed a small, portable, and leak-free flowcell made of PMMA for nanopore experiments. In addition, we developed an in situ functionalizing PLL-g-PEG approach to produce non-sticky nanopores for measuring the volume of diseases-relevant biomarker, such as the Alpha-1 antitrypsin (AAT) protein.

Applications of Healthcare Robots in Combating the COVID-19 Pandemic.

Due to the increasing number of COVID-19 cases, there is a remarkable demand for robots, especially in the clinical sector. SARS-CoV-2 mainly propagates due to close human interactions and contaminated surfaces, and hence, maintaining social distancing has become a mandatory preventive measure. This generates the need to treat patients with minimal doctor-patient interaction.

Early Warning Systems for COVID-19 Infections Based on Low-Cost Indoor Air-Quality Sensors and LPWANs.

During the last two years, the COVID-19 pandemic continues to wreak havoc in many areas of the world, as the infection spreads through person-to-person contact. Transmission and prognosis, once infected, are potentially influenced by many factors, including indoor air pollution. Particulate Matter (PM) is a complex mixture of solid and/or liquid particles suspended in the air that can vary in size, shape, and composition and recent scientific work correlate this index with a considerable risk of COVID-19 infections.

Navigating Virtual Environments Using Leg Poses and Smartphone Sensors.

Realization of navigation in virtual environments remains a challenge as it involves complex operating conditions. Decomposition of such complexity is attainable by fusion of sensors and machine learning techniques. Identifying the right combination of sensory information and the appropriate machine learning technique is a vital ingredient for translating physical actions to virtual movements.