Publications by authors named "Milos I"
Article Synopsis
- The study aimed to assess how a patent foramen ovale and fibroblast growth factor-21 affect core temperature changes in SCUBA divers, while also examining the impact of wetsuit thickness and body measurements on these temperature shifts.
- Involving 31 divers, the research found no significant effect of the patent foramen ovale on temperature responses during dives or on fibroblast growth factor-21 levels.
- Results indicated that the combination of wetsuit thickness and individual body characteristics, like body mass and surface area, plays a significant role in regulating core temperature during diving.
The aim of this study was to investigate the effect of sunlight on the degradation of DNA samples taken from blood stains from different types of surfaces. A blood sample obtained from a single male donor was placed on seven different surfaces (galvanized sheet, iron rod, newspaper, white printer paper, glass, soil, and ceramic panel). Samples were kept, during a 4-week summer period, in a room, but next to an open window.
View Article and Find Full Text PDFMALIGNANT PARAGANGLIOMA NON-RESPONSIVE TO MIBG IN MEN2A SYNDROME.
Acta Endocrinol (Buchar)
January 2022
Introduction: Long-term care (LTC) is organized in a fragmented manner. Payer agencies (PA) receive LTC funds from the agency collecting funds, and commission services. Yet, distributional equity (DE) across PAs, a precondition to geographical equity of access to LTC, has received limited attention.
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- - Multiple endocrine neoplasia type 2 is linked to specific mutations in the RET gene, particularly in exon 10, with limited existing data on their effects.
- - The International RET Exon 10 Consortium conducted a study with 340 subjects to analyze different clinical-risk profiles related to medullary thyroid carcinoma (MTC), pheochromocytoma, and hyperparathyroidism associated with these mutations.
- - Findings revealed varying rates of disease presentation based on specific codon mutations, with a higher penetrance for MTC and a correlation between advanced disease stages and the position of mutations within the gene.
Pancreatic islet cell tumors (ICTs) occur as sporadic neoplasias or as a manifestation of multiple endocrine neoplasia type 1 (MEN1) and von Hippel-Lindau disease (VHL). Molecular classification of ICTs is mandatory for timely diagnosis and surveillance. Systematic comparison of VHL-ICTs and sporadic ICTs has been lacking.
View Article and Find Full Text PDFRET testing in multiple endocrine neoplasia type 2 for molecular diagnosis is the paradigm for the practice of clinical cancer genetics. However, precise data for distinct mutation-based risk profiles are not available. Here, we survey the clinical profile for one specific genotype as a model, TGC to TGG in codon 634 (C634W).
View Article and Find Full Text PDFAn inherited deficiency in beta-galactosidase can result in GM1 gangliosidosis, with several phenotypes of generalized or chronic psychomotor deterioration, as well as in Morquio disease type B, a characteristic mucopolysaccharidosis free of neurological symptoms. We performed mutation analyses in 17 juvenile and adult patients from various European regions with a deficiency in beta-galactosidase and skeletal abnormalities. Fifteen of these had the Morquio B phenotype and have remained neurologically healthy until now while the two others exhibited psychomotor retardation of juvenile onset.
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