Publications by authors named "Milorad Zikic"

Article Synopsis
  • Post-stroke depression (PSD) is a common and serious issue that affects recovery and quality of life after a stroke, often going unnoticed and untreated.
  • The study aimed to identify risk factors for early-onset depression in stroke patients by comparing 30 patients with depression to 30 without, using various diagnostic tools and assessments two weeks post-stroke.
  • Findings revealed that significant predictors of early-onset depression included a history of previous depressive episodes, cognitive impairment, and more severe neurological deficits.
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The aim of the study was to explore whether application of cognitive stimulation in young healthy subjects may improve their cognitive efficiency. The study included 12 healthy young subjects divided into two groups, experimental group and control group. Prior to cognitive stimulation treatment, both groups underwent baseline measurements with selected neuropsychological tests.

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Introduction: This study was aimed at investigating the vascular risk factors associated with the first stroke. It highlighted unfavorable trends in stroke mortality in the region gravitating towards the general hospital in Doboj.

Material And Methods: The study included all patients hospitalized with the diagnosis of first stroke and their main vascular risk factors were explored, both in terms of their importance in the occurrence of stroke, and in terms of gender and age lines.

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In spite of being a common and important complication of stroke, post stroke depression is often overlooked, so its impact on stroke outcome remains under recognized. The aim of the study was to determine the effect of depression on functional outcome and quality of life in stroke patients. The study included 60 patients treated for their first clinical stroke, 30 of them diagnosed with depression and 30 patients without depression.

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Although strokes have been documented since about 3 millennia, they remain today as one of the leading causes of mortality, as well as of subsequent serious long-term physical and mental morbidity, among patients in many different countries all over the world. Greece presents an increase in mortality rates according to World Health Organization, and this fact underlines the need for early diagnosis and treatment, as well as, the need to implement effective prevention strategies for strokes. This review makes an effort to describe the current status of stroke epidemiological features, as well as to present the risk factors prevalent in Greece.

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Stroke is a rapidly developing clinical disturbance of focal or global cerebral function, lasting for more than 1 hour. It is an acute form of symptoms of brain function disorder, with no apparent cause other than vascular origin. It is the final phase of arterial disease, the main cause of disability, and the second leading cause of death.

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In this paper, we report our experience from a prospective study in 40 ischemic stroke patients admitted during the last two years at University Department of Neurology Stroke Unit, Banja Luka Clinical Center, in order to assess the safety and efficacy of thrombolytic therapy, the impact of age, sex and risk factors, and functional outcome at 6 months of intravenous tissue plasminogen activator treatment. According to the National Institutes of Health Stroke Scale, there were 5 mild, 22 moderate and 13 severe stroke cases in the study group. The outcome measures at 6 months of thrombolytic treatment were taken in 38 (100%) patients, yielding a Functional Independent Measure score > or=90 (good clinical outcome) in 21 (52.

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Article Synopsis
  • A study was conducted on 32 patients with relapsing-remitting multiple sclerosis (RRMS) treated with interferon beta-1b over three years, measuring its therapeutic effects and comparing the results with existing literature.
  • The treatment resulted in a 60.5% reduction in annual relapse rates and a significant increase in disability status (EDSS), showcasing interferon beta-1b as an effective disease-modifying therapy.
  • More than half of the patients (53.12%) remained relapse-free during treatment, and the findings align with global research, suggesting the therapy effectively decreases disease activity while presenting few serious side effects.
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Introduction: Neurological disorders are common worldwide, regardless of race, nationality, age, sex, education or social status. They are a major cause of human suffering and mortality. The burden of neurological disorders in the community usually correlates with the proportion of the population aged 65 years and over.

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