Microbiological contaminations of laboratory mice and rats in conventional facilities in Argentina.

Routine microbiological monitoring of rodent colonies in animal facilities is essential to evaluate the health status of the animals used in research studies. In the present study, animals were examined for the presence of selected microbial infections. In order to determine the contamination rates of mice and rats in Argentina, animals from 102 conventional facilities were monitored from 2012 to 2016.

[Pasteurella pneumotropica produces regression of human tumors transplanted in immunodeficiency mice].

The technique of human tumor cell line transplantation in immunodeficient mice is used worldwide as a model for cancer research. In accordance with international recommendations, animals used in biomedical research should be free of microorganisms which can interfere in experimental results; including Pasteurella pneumotropica. The object of this study was to evaluate the interference produced by P.