Background: While Group B Streptococcus (GBS) human colonization and infection has long been suspected as originating from cows, several investigators have suggested that ongoing interspecies GBS transmission is unlikely due to genotyping data demonstrating that human and bovine-derived GBS strains represent mostly distinct populations. The possibility of ongoing transmission between humans and their livestock has not been systematically examined.
Methodology/principal Findings: To examine ongoing interspecies transmission, we conducted a prospective cross-sectional cohort study of 68 families and their livestock.
MUC1, a membrane tethered mucin glycoprotein, is overexpressed and aberrantly glycosylated in >80% of human ductal pancreatic adenocarcinoma. However, the role of MUC1 in pancreatic cancer has been elusive, partly due to the lack of an appropriate model. We report the characterization of a novel mouse model that expresses human MUC1 as a self molecule (PDA.
View Article and Find Full Text PDFA novel configuration of stationary Fourier transform infrared (FTIR) spectrometer is presented. Contrary to classic configurations, the interferometer is directly integrated in the focal plane array (FPA) during its process of fabrication. A first, to the best of our knowledge, demonstration of the spectrometric function has been achieved departing from a well-known structure of an HgCdTe photodetector.
View Article and Find Full Text PDFWe present what is believed to be a novel experimental method to measure the technological parameters (spectral response and quantum yield) of an infrared focal plane array. This method makes original use of a Fourier transform spectrometer, which allows us to simultaneously extract the spectral performances of all pixels from one single set of measurements. The methodology used and the principle of the experimental setup are detailed.
View Article and Find Full Text PDF