Publications by authors named "Millie U M Y Verschuuren"

Article Synopsis
  • Canine flank alopecia (CFA) is a recurring skin condition in dogs, particularly affecting breeds like the Rhodesian Ridgeback, and is characterized by hair loss and skin darkening without inflammation.
  • A study analyzed 24 dogs with CFA and 12 healthy controls, finding evidence of genetic inheritance but no significant differences linked to the melanophylin (MLPH) gene.
  • Though pedigree analysis suggested a genetic influence on CFA, the MLPH gene was not implicated, indicating the need for further research to understand the genetic basis of CFA in these dogs.
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Background: Canine flank alopecia (CFA) is characterized by seasonally recurring noninflammatory, occasionally hyperpigmented alopecia predominantly in the thoracolumbar area. Previous studies suggest that reduced production of endogenous melatonin may play a role in the pathogenesis of this condition, and placebo-controlled studies on the efficacy of preventative melatonin treatment are lacking.

Objective: To evaluate the efficacy of subcutaneous slow-release melatonin implants in the prevention of CFA recurrence.

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