Vet Dermatol
December 2022
Background: Canine flank alopecia (CFA) is characterized by seasonally recurring noninflammatory, occasionally hyperpigmented alopecia predominantly in the thoracolumbar area. Previous studies suggest that reduced production of endogenous melatonin may play a role in the pathogenesis of this condition, and placebo-controlled studies on the efficacy of preventative melatonin treatment are lacking.
Objective: To evaluate the efficacy of subcutaneous slow-release melatonin implants in the prevention of CFA recurrence.