The Role of a Clinical Pharmacist in the Identification of Potentially Inadequate Drugs Prescribed to the Geriatric Population in Low-Resource Settings Using the Beers Criteria: A Pilot Study.

Population aging is a global phenomenon. Each country in the world faces an increased number of older persons in the total population. With aging, a high prevalence of multiple chronic diseases occurs, leading to the use of complex therapeutic regimens and often to polypharmacy.

The Declining Use of Opioids at a Level 1 Trauma Center.

Background: The epidemic of opioid-related overdose in the United States prompted a public health response that included implementation of opioid prescribing guidelines and restrictions. Such directives, however, were not applicable to hospitalized trauma patients. We hypothesized that although prescribing mandates did not apply to hospitalized trauma patients, inpatient opioid administration had nonetheless decreased over time.

A Questionnaire for Rating Health-related Quality of Life.

Background: Translations of instruments for measuring quality of life developed in certain, mostly more developed, parts of the world usually do not cover regionally specific aspects of health-related quality of life, even after transcultural validation. The aim of this study was to develop and validate a reliable questionnaire in Serbian, Croatian, Bosnian, and Montenegrin languages suitable for measuring health-related quality of life in adults.

Methods: The study was of a cross-sectional type, assessing the reliability and validity of a newly developed questionnaire for measuring health-related quality of life (HRQoL) in adults residing in western Balkan states (WB-HRQoL).

Altered Mental Status in the Emergency Department - When to Consider Anti-LGI-1 Encephalitis: Case Report.

Introduction: Anti-leucine-rich glioma inactivated-1 (LGI-1) is one of few antibodies implicated in limbic encephalitis, a syndrome that can result in permanent neurological symptoms if left untreated.

Case Report: We present a patient with dystonic seizures, progressive cognitive decline, psychiatric symptoms and short-term memory loss, and mild hyponatremia diagnosed with anti-LGI-1 antibody limbic encephalitis.

Conclusion: There are few reports in the emergency medicine community describing anti-LGI-1 antibody limbic encephalitis.

Mechanisms of skin moisturization with hyperharmonized hydroxyl modified fullerene substance.

Background: Hyper Harmonized Hydroxyl Modified Fullerene Substance (3HFWC ) establishes hydrogen bonds with the surrounding water molecules and organizes them in clusters with the liquid crystalline state, similar to the properties of water surrounding the biomolecules.

Aims: To investigate the moisturizing properties of hyperharmonized fullerenol-3HFWC as an emulsion O/W ingredient on the skin.

Patients/methods: We have analyzed the reflexion of the blue light from the skin, in vivo, with different levels of moisturization and compared the influence of three groups of cosmetic products (with various active ingredients, 3HFWC or water in same percentage in the "vehiculum") on skin moisturization by measuring paramagnetic/diamagnetic properties by Optomagnetic Imaging Spectroscopy.

Traumatic penetrating arteriovenous fistulas: a collective review.

Introduction: Traumatic penetrating arteriovenous fistulas (AVFs) are very rare. The majority of these injuries occur secondary to penetrating trauma. Objectives of this study: review their incidence, clinical presentation, radiologic identification, management, complications and outcomes.

Penetrating Internal and Common Carotid Artery Injuries Shunts versus no shunts during repair effect on neurological outcomes.

Background: Penetrating Carotid artery injuries are rarely encountered even in busy in urban Trauma Centers. Repair is preferred over ligation for Internal (IC) and Common Carotid (CC) arteries. To date, the use of temporary shunts correlated to neurological outcomes has not been reported.

A systematic review and individual patient data meta-analysis of heart failure as a rare complication of traumatic arteriovenous fistulas.

Objective: Traumatic arteriovenous fistulas (AVFs) are rare. The vast majority occur secondary to penetrating injuries. High-output cardiac failure is a well-recognized serious complication of AVFs, associated with high morbidity and mortality.

Quality of Life Indicators in Patients Operated on for Breast Cancer in Relation to the Type of Surgery-A Retrospective Cohort Study of Women in Serbia.

Quality of life (QoL) after breast cancer surgery is an important public health issue. The aim of this study was to determine the relationship between the levels of perceived quality of life in patients operated on for breast cancer in relation to the type of surgery, using the standardized questionnaires. We assessed 425 women after surgery for breast cancer.

Popliteal artery injuries. Less ischemic time may lead to improved outcomes.

Background: Popliteal artery injuries are rare. They have high amputation rates.

Objectives: To report our experience, identify predictors of outcome; mechanism of injury (MOI), Mangled Extremity Severity Score (MESS) score and length of ischemic time.

Brachial Artery Injuries Operative Management and Predictors of Outcome.

Background: Brachial artery injuries are rare. The objectives of the study are to report our experience and identify predictors of outcome. The hypothesis of the study is that maintaining ischemic times less than six hours results in improved outcomes.

A systematic review of penetrating extracranial vertebral artery injuries.

Background: Penetrating vertebral artery injuries (VAIs) are rare. Because of their rarity, complex anatomy, and difficult surgical exposures, few surgeons and trauma centers have developed significant experience with their management. The objectives of this study were to review their incidence, clinical presentation, radiologic identification, management, complications, and outcomes and to provide a review of anatomic exposures and surgical techniques for their management.

Influence of hyper-harmonized fullerene water complex on collagen quality and skin function.

Background: Fullerene water complex establishes the optimal order and function of biomolecules in natural, biophysical way by transducing the signal through water hydrogen bonds to biomolecules.

Objectives: This paper considers the effects of the patented hyper-harmonized-hydroxylated fullerene water complex (3HFWC) on biophysical properties of the skin collagen molecules.

Method: Optomagnetic imaging spectroscopy (OMIS) has been used for the analysis of the biophysical skin properties (diamagnetic/paramagnetic) after applying three groups of different cosmetic products.

Trends in thyroid cancer incidence and mortality in Central Serbia, 1999-2014.

Introduction: Thyroid cancer (TC) is the most common malignant disease of the endocrine system. The incidence of the TC has been increasing worldwide, especially in female population. However, mortality from TC is low in both males and females.

The first comparative double-blind trial on efficacy and safety of ergotamine based five-component combination and sumatriptan in migraine without aura.

Background: Dihydroergotamine or ergotamine are the most effective preparations for aborting acute attacks of migraine without aura.

Objective: The aim of our study was to compare the efficacy and safety of ergotamine based five-component drug combination and sumatriptan in the treatment of moderate to severe acute attacks of migraine without aura.

Methods: The study was designed as a randomized, double-blind, double-dummy, placebo-controlled, parallel arm, multi-center clinical trial.

SUN PROTECTION BEHAVIOR AMONG ADOLESCENTS - A COMPARATIVE STUDY CONDUCTED IN 2008 AND 2012.

Introduction: Adolescents should limit their exposure to sun and apply sun protection measures. The purpose of this study was to establish changes in adolescents behavior regarding sun protection beetwen years 2008 and 2012, as well as to assess the impact of sex and skin photo-type on behavior in order to suggest positive sun protection behavior practised in other countries and to improve educational program.

Material And Methods: An original, tailormade questionnaire (about the skin types, exposure to sun and the use of sunbed) was distributed among 16 and 17-year-old students in high school in Belgrade, Serbia to be fulfilled within the framework of the educational project in.

The impact of education on adolescents' sun behavior: experiences from Serbia.

Introduction: In Serbia, there have been no broad campaigns or educational programs focused on adolescents' sun protection.

Objective: The aim of the study was to assess whether an educational program would have impact on changes of attitudes and sun-protective behaviors of high school students. More specific aim was to examine whether sex and age differences in sun behavior exists.

Hemorrhagic complications of thrombolytic therapy.

Stroke is the most frequent neurological disorder, and the most common cause of severe disability compared to other diseases. Recombinant tissue plasminogen activator (rt-PA) is the only approved specific therapy for acute ischemic stroke. Hemorrhage is a significant complication of thrombolytic treatment.

Our experience with thrombolytic therapy -- preliminary report.

Stroke is a rapidly developing clinical disturbance of focal or global cerebral function, lasting for more than 1 hour. It is an acute form of symptoms of brain function disorder, with no apparent cause other than vascular origin. It is the final phase of arterial disease, the main cause of disability, and the second leading cause of death.

Vascular dementia: clinical and neuroradiological correlation.

All stroke patients admitted to Banjaluka Clinical Centre during one year were evaluated by the standard protocol during the hospitalization and three months after the stroke. It included clinical, functional and neuropsychological examination and neuroimaging. Dementia was diagnosed according to the criteria of National Institute of Neurological Disorders and Stroke-Association Internationale pour la Recherche et l'Enseignement en Neurosciences.

[Influence of demographic and socioeconomic characteristics on the quality of life].

Introduction: The quality of life is a multidimensional concept, which is best expressed by the subjective well-being. Evaluation of the quality of life is the basis for measuring the well-being, and the determination of factors that determine the quality of life quality is the basis for its improvement.

Objective: To evaluate and assess the determinants of the perceived quality of life of group distinguishing features which characterize demographic and socioeconomic factors.

[Characteristics of reproductive health of women in their generative age].

Introduction: Any research of reproductive health has to encompass the relevant connotations of this complex term. In order to establish relevant multidimensional characteristics, it is necessary to assess intercorrelations of the characteristics most commonly used to describe it.

Objective: Our aim was to describe the characteristics of reproductive health and to establish their significance in describing this term.

[Determinants of the most significant characteristics of reproductive health].

Introduction: Reproductive health of women is determined by females' demographic and socio-economic characteristics, their behaviour, and the complex of environmental factors.

Objective: The paper examines the predictive impact of personal and environmental characteristics, health and healthcare characteristics regarding the most important aspects of reproductive health.

Methods: From a sample of 2,718 women, aged 20-49 years, we collected information on various characteristics using a structured questionnaire.

Functional outcome after thrombolytic therapy.

In this paper, we report our experience from a prospective study in 40 ischemic stroke patients admitted during the last two years at University Department of Neurology Stroke Unit, Banja Luka Clinical Center, in order to assess the safety and efficacy of thrombolytic therapy, the impact of age, sex and risk factors, and functional outcome at 6 months of intravenous tissue plasminogen activator treatment. According to the National Institutes of Health Stroke Scale, there were 5 mild, 22 moderate and 13 severe stroke cases in the study group. The outcome measures at 6 months of thrombolytic treatment were taken in 38 (100%) patients, yielding a Functional Independent Measure score > or=90 (good clinical outcome) in 21 (52.

Irritable bowel syndrome, anxiety, depression and personality characteristics.

Background: Numerous studies have suggested that 54%-100% of patients with IBS may have associated psychiatric illness and personality pathology. This transversal controlled study was realized in order to evaluate anxiety and depression levels, as well as the personality characteristics of patients with IBS and to compare the results obtained with patients with episodes of depression and healthy individuals.

Subjects And Methods: The experimental group consisted of 30 IBS patients, while two control groups consisted of the same number of inpatients with episodes of depression and healthy individuals from the general population.