Common variant in myocilin gene is associated with high myopia in isolated population of Korcula Island, Croatia.

Aim: To study the association between genetic variants in myocilin and collagen type I alpha 1 genes and high myopia in an isolated island population.

Methods: A total of 944 examinees from the genetic epidemiology study conducted on the island of Korcula, Croatia, were included in the study. We selected 2 short nucleotide polymorphisms (SNP) available in our genome-wide scan set of SNPs that were previously associated with high myopia and used them to replicate previous claims of possible association.