Publications by authors named "Milisha Koh A Magesvaran"
J Biomol Struct Dyn
July 2021
Article Synopsis
- The interaction between the anticancer drug saracatinib (SCB) and human serum albumin (HSA) was studied using fluorescence and absorption spectroscopy, along with computational methods.
- Analysis indicated that SCB forms a complex with HSA, highlighted by temperature dependence and absorption spectrum changes.
- Results showed moderate binding affinity between SCB and HSA, with stabilization from hydrophobic, van der Waals, and hydrogen bonds, while SCB also protected HSA from thermal denaturation and preferred binding at Sudlow's site I.
