Transient ultrasound stimulation has lasting effects on neuronal excitability.

Background: Transcranial ultrasound stimulation can acutely modulate brain activity, but the lasting effects on neurons are unknown.

Objective: To assess the excitability profile of neurons in the hours following transient ultrasound stimulation.

Methods: Primary rat cortical neurons were stimulated with a 40 s, 200 kHz pulsed ultrasound stimulation or sham-stimulation.