Chemical Profile and Antioxidant and Antimicrobial Activity of L. Dried Fruit Commercially Available in Serbia.

The aim of this work was to give as much information as possible on dried fruit that is commercially available in Serbia. In order to provide the chemical composition, the UHPLC-DAD-ESI-MS method was employed for both polar and non-polar extracts of samples obtained with a solvent mixture consisting of hexane, acetone, and ethanol in a volume ratio of 2:1:1, respectively, and 0.05% (/) butylated hydroxytoluene.

Consistency between causality assessments obtained with two scales and their agreement with clinical judgments in hepatotoxicity.

Purpose: Reliability and usefulness of scales for causality assessment in hepatotoxicity have not been fully explored. The goal of this study was to examine consistency between causality assessments obtained with two commonly used scales and their agreement with initial clinical assessments in hepatotoxicity reported in Serbia, and to review usefulness of these scales.

Methods: We compared the two scales (CIOMS/RUCAM and NARANJO) in 80 cases reported during 1995-2009.