Publications by authors named "Milena Freddi"
Article Synopsis
- * A total of 40 patients underwent FCH-PET/CT, revealing high sensitivity (93.3%) and overall accuracy (87.8%) for identifying lesions, with 42 of 48 lesions shown to have true-positive uptake.
- * The researchers found that higher levels of parathyroid hormone (PTH) and the size of the parathyroid glands were significantly correlated with the PET scan results, indicating that these factors could influence imaging outcomes.
Background: To evaluate the efficacy of the use of flow cytometry (FC) immunophenotyping together with fine-needle aspiration cytology (FNAC) in the diagnosis of thyroid lymphoma.
Methods: FC was performed in parallel with FNAC in 35 samples of suspected thyroid lymphoma over a 12 years period. Results were correlated with histological or molecular findings and follow-up, when available.
Cytological examination of material from fine-needle aspiration biopsy is the mainstay of diagnosis of thyroid nodules, thanks to its remarkable accuracy and scarcity of complications. However, follicular lesions (also called indeterminate lesions or Thy3 in the current classification), a heterogeneous group of lesions in which cytology is unable to give a definitive diagnosis to, represent its main limit. Elastography has been proposed as a potential diagnostic tool to define the risk of malignancy in the aforementioned nodules, but at present there is no conclusive data due to the small number of specifically addressed studies and the lack of concordance among them.
View Article and Find Full Text PDFBackground: Extensive resection of the tumor has been associated with better survival of anaplastic thyroid carcinoma (ATC) patients. However, surgery is not the rule for ATC patients with distant metastases at the time of diagnosis (stage IV-C), regardless of tumor resectability. The aim of this work was to explore the potential role of surgery in ATC patients, including those in stage IV-C.
View Article and Find Full Text PDFPurpose: In differentiated thyroid carcinoma (DTC), complete resection of local disease provides the longest survival and the best palliation. In pursuit of this goal, segmental tracheal or laryngotracheal resection can be performed on patients with DTC invading the airway. The study summarizes the technical aspects of the intervention and analyzes its results in eight patients.
View Article and Find Full Text PDFAim Of The Study: To retrospectively investigate the patients' views of surgical treatment of Graves' hyperthyroidism.
Methods: One hundred two patients were included in the study and submitted to extensive subtotal thyroidectomy or total thyroidectomy between 1993-2003. Data were acquired from the responses to a questionnaire, that was completed by 83 patients.