U-shaped relationship between vitamin D levels and long-term outcome in large cohort of survivors of acute myocardial infarction.

Background: Previous studies in the setting of patients with acute myocardial infarction (AMI) have demonstrated that hypovitaminosis D is associated with increased mortality risk during a follow-up whose median did not exceed two years.

Objective: To evaluate the impact of vitamin D levels on long-term mortality in patients with AMI.

Results: In our study 477 patients with AMI were included.

Factor-V HR2 haplotype and thromboembolic disease.

Objectives: The objective of this study is to evaluate the prevalence of HR2 polymorphism among patients with pulmonary embolism (PE) and healthy subjects.

Background: Polymorphism in the factor V gene named HR2 has been described as a possible risk factor for venous thromboembolism (VTE) development. Contradictive results on this association have been reported.