Publications by authors named "Milena C N Monteiro"
J Chem Neuroanat
November 2022
Article Synopsis
- Parkinson's disease (PD) is a neurodegenerative disorder linked to the loss of dopamine-producing neurons, with animal models typically using younger subjects, resulting in potential biases in research.
- A study was conducted using both adult and elderly male rats to assess the impact of age on parkinsonism induced by reserpine (RES), with evaluations based on behavior tests and weight assessments over a 30-day period.
- Results indicated that elderly rats experienced more severe catalepsy and slower symptom development than adult rats, while both age groups suffered weight loss, highlighting significant differences in how PD manifests with age.
