Prostate cancer is estimated to be the second most common malignancy in men in the USA in 2020 and represents the second highest mortality from cancer behind lung and bronchial neoplasms. Management of advanced prostate cancer is evolving. Medical androgen deprivation therapy is currently a cornerstone of therapy for prostate cancer; however molecular mechanisms of resistance have emerged leading to castration-resistant prostate cancer that is proliferation of prostate cancer in the setting of low testosterone (< 50 ng/dl).
View Article and Find Full Text PDFTumor lysis syndrome (TLS) is the phenomenon of metabolic derangements that typically follows the initiation of cytotoxic chemotherapy. Metabolic disturbances include hyperphosphatemia, hyperkalemia, hyperuricemia and hypocalcemia. Hematological malignancies are associated with spontaneous TLS (STLS), which is cell lysis in the absence of chemotherapy.
View Article and Find Full Text PDFObjective: 1) Evaluate the accuracy of financial disclosures reporting by research presenters and moderators at the American Neurotology Society Spring meetings between 2014 and 2016. 2) Tabulate the reported monetary value of undisclosed financial relationships. 3) Determine the degree of compliance to the standards put forth by the Accreditation Council for Continuing Medical Education.
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