Publications by authors named "Milan Ms Obradovic"
Article Synopsis
- Metastatic colonization of distant organs is a major cause of death in solid cancers, and this study identifies a critical pathway in aggressive basal-like breast cancer involving the enzyme NNMT.
- NNMT enhances cancer cell flexibility and is linked to worse outcomes in patients; when removed in mouse models, it significantly reduces metastasis.
- The study reveals that NNMT influences specific genetic changes, promoting the expression of PRDM5, which is crucial for collagen production and metastatic spread.
