Inhibition of azole-resistant Candida albicans ATPase and oxidoreductase activity by a flavonoid from Dalea elegans.

Background: The flavonoid 2', 4'-dihydroxy-5'-(1''', 1'''-dimethylallyl)-8-prenylpinocembrin (8PP) obtained from Dalea elegans roots inhibits cell growth and cdr pumps, in addition to reversing fluconazole (FCZ) resistance in Candida albicans.

Aims: To study the effects of 8PP and FCZ on cdr-associated ATPase and cell energy generation in azole-resistant C. albicans planktonic cultures.

[Inhibitory effect of diethylstilbestrol on clinical strains of Candida albicans susceptible and resistant to azoles].

Background: Candida albicans is a microorganism frequently involved in several infections; the patient's oral cavity, caries niches or periodontal disease can sometimes be the reservoir.. The fungal resistance to the available treatments, among other reasons, has led to the search for new antifungal alternatives.

Effects of tamoxifen on periodontal disease and Candida albicans of patients with breast cancer and other pathologies.

Unlabelled: Candida albicans is involved in periodontal disease, which is influenced by sex hormones.

Aim: To study the effects of the estrogen antagonist tamoxifen (TAM) on periodontal disease of oncological patients; clinical oral strains of C. albicans.