Publications by authors named "Mikulski M"

Introduction And Objective: Surface electromyography (sEMG) measurements are a valid method for sublesional muscle activity following spinal cord injury (SCI). In the literature there are few reports evaluating the effect of robotic assisted gait training (RAGT) on the sEMG properties change in SCI patients. The aim of this study was to evaluate the influence of RAGT on observed change of sEMG, and in 64 incomplete SCI patients in the sub-acute stage in relation to functional scales.

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Postoperative critical care management of congenital heart disease patients requires prompt intervention when the patient deviates significantly from clinician-determined vital sign and hemodynamic goals. Current monitoring systems only allow for static thresholds to be set on individual variables, despite the expectations that these signals change as the patient recovers and that variables interact. To address this incongruency, we have employed statistical process monitoring (SPM) techniques originally developed to monitor batch industrial processes to monitor high-frequency vital sign and hemodynamic data to establish multivariate trajectory maps for patients with d-transposition of the great arteries following the arterial switch operation.

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Article Synopsis
  • - A chitosan-based thermosensitive hydrogel (CH) enriched with hydroxyapatite (HAp) and poly(lactic acid) (PLDLLA) was developed to promote bone regeneration while exhibiting antimicrobial properties.
  • - The modified hydrogels showed enhanced mechanical strength and confirmed non-cytotoxicity in tests with osteoblast-like cells, making them suitable for medical applications.
  • - A clinical trial demonstrated the hydrogel's effectiveness in treating chronic inflammation in dental tissues, highlighting its safety and bone-forming capabilities through detailed analysis of pre- and post-surgery imaging.
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Background: The aim of the study was to assess the inter-rater and intra-rater agreement of measurements performed with the Luna EMG (electromyography) multifunctional robot, a tool for evaluation of upper limb proprioception in individuals with stroke.

Methods: The study was conducted in a group of patients with chronic stroke. A total of 126 patients participated in the study, including 78 women and 48 men, on average aged nearly 60 years (mean = 59.

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Objectives: Patients with dextro-transposition of the great arteries (d-TGA) frequently undergo balloon atrial septostomy (BAS) prior to the arterial switch operation (ASO) to promote atrial-level mixing. Balloon atrial septostomy has inherent risks as an invasive procedure and may not always be necessary. This study revisits the routine utilization of BAS prior to ASO.

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Background: Achalasia is an esophageal motility disorder with three subtypes based on manometry that can treated with per-oral endoscopic myotomy (POEM). With the advent of impedance planimetry (EndoFLIP®), we hypothesized the three achalasia subtypes would have different pre-POEM EndoFLIP® diameter and distensibility index (DI) measurements but would be similar after POEM.

Methods: A single-institution, retrospective review of consecutive POEM cases by a single surgeon-endoscopist team from 04/07/2017 to 08/28/2023.

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This study details the design, fabrication, clinical trials' evaluation, and analysis after the clinical application of 3D-printed bone reconstruction implants made of nHAp@PLDLLA [nanohydroxyapatite@poly(L-lactide--D,L-lactide)] biomaterial. The 3D-printed formulations have been tested as bone reconstruction in 3 different medical cases, including frontal lobe, mandibular bone, and cleft palate reconstructions. Replacing one of the implants after 6 months provided a unique opportunity to evaluate the post-surgical implant obtained from a human patient.

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Background: Paediatric cardiac electrophysiologists are essential in CHD inpatient care, but their involvement is typically limited to consultation with individual patients. In our integrated heart centre, an electrophysiologist reviews all cardiac inpatient telemetry over the preceding 24 hours and participates in daily multidisciplinary morning report. This study investigates the impact of the strategy of consistent, formalised electrophysiologist presence at multidisciplinary morning report.

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In this paper, surface electromyography (sEMG) is used to gather the activation neural signal from muscles during an indoor rowing exercise. The exercise was performed by professional athletes and amateur non-athletes. The data acquisition and processing are described to obtain a set of parameters: number of cycles, average cycle time, cycle time standard deviation, fatigue time, muscle activation time, and muscle energy.

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Article Synopsis
  • - The study reviewed the hemodynamic effects of packed red blood cell transfusions in infants post-arterial switch operation, capturing real-time data from vital sign monitors over a specific period before, during, and after the transfusions.
  • - A total of six patients received 10 transfusions, showing significant increases in systolic and mean arterial blood pressures (5-12.5%) three hours after the transfusions, along with a 6.2% rise in renal near-infrared spectroscopy readings.
  • - No notable changes were found in ventilation, vasoactive support, or oxygen balance laboratory values, highlighting the need for further understanding of the overall efficacy of these transfusions.
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Background: The Berlin Heart EXCOR® (BHE) can bridge children with severe heart failure to transplantation, but some are successfully weaned and spared transplantation. This study seeks to identify characteristics of children amenable to successful explantation with BHE support.

Methods: Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines were used.

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BACKGROUND Proprioception, the body's ability to perceive its own position and movement, is fundamental for motor control and coordination. Reliable assessment tools are essential, particularly for conditions affecting proprioceptive function. This study aimed to evaluate the external and internal compliance of the Luna EMG -multifunction robotic device in assessing proprioception.

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Background: Per-oral endoscopic myotomy (POEM) has become an accepted minimally invasive alternative to Heller myotomy for the treatment of achalasia and other disorders of esophageal dysmotility. One associated adverse event is the inadvertent creation of capnoperitoneum. A proposed mechanism is that extension of the submucosal tunnel below the esophageal hiatus and onto the gastric wall leads to transmural perforation.

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Article Synopsis
  • Multiple laparotomies, immunosuppressive therapy, and nutritional issues increase the risk of incisional hernias in inflammatory bowel disease (IBD) patients, prompting a study on repair techniques and complications through minimally invasive methods.
  • A review of IBD patients over 14 years showed that 39.7% experienced hernia recurrence, with differing rates depending on the type of mesh placement; notably, mesh placed intraperitoneally had a 35.1% recurrence rate.
  • The study concluded that minimally invasive repair approaches result in fewer complications than open repairs, and recurrence rates were significantly lower when performed by specialized hernia surgeons compared to colorectal surgeons.
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The aim of this study was to compare the effectiveness of traditional neurological rehabilitation and neurological rehabilitation combined with a rehabilitation robot for patients with post-COVID-19 fatigue syndrome. Eighty-six participants transferred from intensive care units due to post-viral fatigue after COVID-19 were randomly divided into two groups: the intervention group and the control group. The control group received standard neurological rehabilitation for 120 min a day, while the intervention group received the same neurological rehabilitation for 75 min a day, complemented by 45 min of exercises on the rehabilitation robot.

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In this study, we present the discovery and pharmacological characterization of a new series of 6-piperazinyl-7-azaindoles. These compounds demonstrate potent antagonism and selectivity against the 5-HT receptor. Our research primarily focuses on optimizing the lead structure and investigating the structure-activity relationship (SAR) of these compounds.

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Objectives: Marfan syndrome is a heritable connective tissue disorder with significant aortopathy and conveys substantial cardiovascular morbidity. This study characterizes the mortality and morbidities of thoracic aortic interventions (TAI) in the Marfan syndrome population in the state of Texas from 2009 to 2019.

Methods: A retrospective review of the Texas Inpatient Discharge Dataset from 1 January 2009 to 31 December 2019.

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Article Synopsis
  • The study explores the effects of submucosal tunnel (SMT) dissection on the success of per-oral endoscopic myotomy (POEM) for treating esophageal dysmotility, specifically looking at changes in luminal diameter and distensibility index (DI).
  • Researchers analyzed data from 66 POEM patients and found that SMT dissection alone led to significant changes in luminal diameter and DI, accounting for 38% and 30% of the total changes seen with complete POEM, respectively.
  • The results indicate that while SMT dissection impacts esophageal dimensions, the full benefits of POEM come from additional factors, suggesting that the submucosa could be targeted for improved treatments in achal
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Objective: The pathway to become a congenital heart surgeon (CHS) is challenging and unpredictable. Previous voluntary manpower surveys have shed partial light on this problem but have not included all trainees. We believe that this arduous journey merits more attention.

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Background: Neonatal congenital atrioventricular block (nCAVB) is rare, causes bradycardia, confers high mortality, and frequently requires pacing. In-hospital outcomes and pacemaker management in nCAVB are limited.

Objectives: The purpose of this study was to analyze pacing and outcomes of nCAVB with and without congenital heart disease (CHD) using a multicenter database.

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Objective: To evaluate the impact of an innovative leadership development initiative in the core surgery clerkship that addressed duty hours compliance and time-off requests.

Design: A combination of deductive and inductive analysis of medical student reflections written after rotating on Acute Care Surgery over 2 academic years (2019-2020 and 2020-2021) was performed. Reflections were part of criteria to receive honors and a prompt was given to discuss their experience in creating their own call schedules.

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Introduction: The COVID-19 pandemic has significantly impacted the diagnosis of breast cancer (BC). With a large Hispanic/Latinx population, early revocation of mask mandates, and lower vaccination rate than many other states, this study explores the relationship between COVID-19 and the presentation and diagnosis of BC patients in the unique socio-politico-economic context of Central Texas.

Methods: This study is a retrospective review of the Seton Medical Center Austin tumor registry for BC patients from March 1, 2019 to March 2, 2021.

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Pericardial effusion (PCE) is a significant complication after pediatric cardiac surgery. This study investigates PCE development after the arterial switch operation (ASO) and its short-term and longitudinal impacts. A retrospective review of the Pediatric Health Information System database.

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