Publications by authors named "Mikko Mikkonen"

Our surrounding auditory environment has a dramatic influence on the development of basic auditory and cognitive skills, but little is known about how it influences the recovery of these skills after neural damage. Here, we studied the long-term effects of daily music and speech listening on auditory sensory memory after middle cerebral artery (MCA) stroke. In the acute recovery phase, 60 patients who had middle cerebral artery stroke were randomly assigned to a music listening group, an audio book listening group, or a control group.

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We know from animal studies that a stimulating and enriched environment can enhance recovery after stroke, but little is known about the effects of an enriched sound environment on recovery from neural damage in humans. In humans, music listening activates a wide-spread bilateral network of brain regions related to attention, semantic processing, memory, motor functions, and emotional processing. Music exposure also enhances emotional and cognitive functioning in healthy subjects and in various clinical patient groups.

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The auditory sensory-memory mechanisms in the human brain were investigated using the mismatch negativity (MMN) component of the event-related potential. MMNs were recorded to stimuli deviating from the repetitive standard stimuli simultaneously either in one or two features (frequency, intensity). If the processing of these two features is independent of each other, the MMN to the double deviant should equal the sum of the MMNs elicited by the corresponding single deviants.

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