Publications by authors named "Mikkel Thunestvedt Hansen"

Purpose: This study aimed to investigate the validity and applicability of a non-exercise estimation of cardiorespiratory fitness using resting seismocardiography (SCG eV̇Opeak) in people with overweight and obesity before and after a 14-week lifestyle intervention.

Methods: The study was carried out at a Folk high school that offers 14-week courses on lifestyle changes where participants live at the school and voluntarily participate in daily lectures and activities. Sixty-seven men and women with age and body mass index between 18 and 70 years and 25-50 kg·m were tested at baseline, and 52 had a follow-up test after 14 weeks.

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A non-exercise method equation using seismocardiography for estimating V̇Opeak (SCG V̇Opeak) has previously been validated in healthy subjects. However, the performance of the SCG V̇Opeak within a trained population is unknown, and the ability of the model to detect changes over time is not well elucidated. Forty-seven sub-elite football players were tested at the start of pre-season (SPS) and 36 players completed a test after eight weeks at the end of the pre-season (EPS).

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Purpose: In Football, the high-intensity running bouts during matches are considered decisive. Interestingly, recent studies showed that peak fat oxidation rates (PFO) are higher in football players than other athletes. This study aimed to investigate whether PFO increases following a pre-season.

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Article Synopsis
  • The study aimed to explore how prolonged exercise impacts liver fat (LF) and visceral adipose tissue (VAT) in well-trained older men, comparing their health metrics with those of recreationally active peers.
  • After cycling 2,558 km over 16 days, results showed that well-trained older men had lower VAT and a trend towards lower LF compared to a control group, with LF significantly decreasing post-exercise.
  • Ultimately, while repeated exercise reduced LF, it did not affect VAT, fat mass, or lean mass, indicating that aerobic capacity relates to lower LF and VAT levels in older active individuals.
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Background: The aim of this study was to investigate the effect of prolonged endurance exercise on adipose tissue inflammation markers and mitochondrial respiration in younger and older men.

Methods: "Young" (aged 30 years, n = 7) and "old" (aged 65 years, n = 7) trained men were exposed to an exercise intervention of 15 consecutive days biking 7 to 9 hours/day at 63% and 65% of maximal heart rate (young and old, respectively), going from Copenhagen, Denmark to Palermo, Italy. Adipose tissue was sampled from both the gluteal and abdominal depot before and after the intervention.

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Cardiorespiratory fitness measured as ˙VOmax is considered an important variable in the risk prediction of cardiovascular disease and all-cause mortality. Non-exercise ˙VOmax prediction models are applicable, but lack accuracy. Here a model for the prediction of ˙VOmax using seismocardiography (SCG) was investigated.

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Aim & Methods: Extreme endurance exercise provides a valuable research model for understanding the adaptive metabolic response of older and younger individuals to intense physical activity. Here, we compare a wide range of metabolic and physiologic parameters in two cohorts of seven trained men, age 30 ± 5 years or age 65 ± 6 years, before and after the participants travelled ≈3000 km by bicycle over 15 days.

Results: Over the 15-day exercise intervention, participants lost 2-3 kg fat mass with no significant change in body weight.

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The peak fat oxidation rate (PFO) and the exercise intensity that elicits PFO (Fat ) are associated with endurance performance during exercise primarily involving lower body musculature, but it remains elusive whether these associations are present during predominant upper body exercise. The aim was to investigate the relationship between PFO and Fat determined during a graded exercise test on a ski-ergometer using double-poling (GET-DP) and performance in the long-distance cross-country skiing race, Vasaloppet. Forty-three healthy men completed GET-DP and Vasaloppet and were divided into two subgroups: recreational (RS, n = 35) and elite (ES, n = 8) skiers.

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Introduction: The scientific outcome of Health Science PhD theses has been questioned by arguments suggesting that strategic motives are important for graduationamong clinical PhD graduates which may compromise scientific output and quality. This study aimed to investigate the scientific outcome of clinical PhD theses.

Methods: A total of 841PhD theses from the Department of Clinical Medicine, University of Copenhagen, were concluded in 2013-2017.

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Peak fat oxidation rate (PFO) and the intensity that elicits PFO (Fat ) are commonly determined by a validated graded exercise test (GE) on a cycling ergometer with indirect calorimetry. However, for upper body exercise fat oxidation rates are not well elucidated and no protocol has been validated. Thus, our aim was to test validity and inter-method reliability for determination of PFO and Fat in trained men using a GE protocol applying double poling on a ski-ergometer.

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