Publications by authors named "Mikhail Yu Volkov"
An electrospark technology has been developed for obtaining a colloidal solution containing nanosized amorphous carbon. The advantages of the technology are its low cost and high performance. The colloidal solution of nanosized carbon is highly stable.
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- The study focuses on developing biodegradable polymer coatings for stents using poly(lactic-co-glycolic acid) (PLGA), which can release large molecules like prourokinase over time.
- The coatings exhibit significant elasticity and tensile strength, degrade slowly in isotonic solutions (0.05%-1.0% per day), and maintain around 90% enzymatic activity of prourokinase during release.
- Testing in animals showed no short-term toxicity or complications post-surgery, with minimal traces of PLGA found after 60 days, indicating the coatings are safe and effective for medical use.