Publications by authors named "Mikhail A Stepanov"

Peroneal neuropathy is one of the complications of orthopaedic leg lengthening. Methods of treatment include slowing of distraction and decompression both of which may lead to additional complications. The purpose of this study was to analyse the changes in histologic peroneal nerve structure during experimental orthopaedic lengthening using various modes of manual or automatic distraction.

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Reactive and adaptive changes in mechanically uninjured nerves during fracture healing have not been studied previously although the status of innervation is important for bone union and functional recovery. This study explores whether subclinical nerve fibre degeneration occurs in mechanically uninjured nerves in an animal fracture model and to quantify its extent and functional significance. Twenty-four dogs were deeply anaesthetized and subjected to experimental tibial shaft fracture and Ilizarov osteosynthesis.

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Introduction: Muscle regeneration is promoted when the Ilizarov method is used for limb lengthening and deformity correction, but the regenerative ability of muscles decreases when achieving large amounts of elongation. Much research has been dedicated to studying the capabilities of muscles under lengthening, but no reports are available that investigate the muscle metabolism. We supposed that energy turnover would be activated in skeletal muscles under lengthening as a response to distraction, and the activity of the energy turnover would grow in proportion to the increase in the distraction rate or amount.

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Purpose: This pilot study aimed to test the theory that different lengthening methods affect the microscopic structure of knee joint synovium in diverse ways.

Methods: This was a descriptive and analytical cross-sectional study of synovium carried out in two experimental models of canine leg lengthening using the Ilizarov fixator. Group 1 (n = 6) used manual gradual distraction most commonly used in clinical practice at one millimetre/day divided into four equal increments, 0.

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