Difluoroboron Complexes as Versatile Precursors for Steroid Modification. Lumiestrone-Based Steroid Derivatives: Synthesis and Structural Studies.

A preparation method for steroid-based difluoroboron complexes has been developed using lumiestrone as a steroid example. Previously inaccessible lumiestrone-based difluoroboron complexes annulated at positions 16 and 17 of the D ring have been prepared. Such difluoroboron complexes may have large synthetic potential for heterofunctionalization of steroids at the D ring.

New Aspects of the Reaction of Thioacetamide and N-Substituted Maleimides.

N-Arylmaleimides are universal substrates for the synthesis of various heterocyclic compounds with a wide spectrum of biological activity. However, their reactions with thioacetamides have not been comprehensively studied. We studied the reactions of thioacetamide with N-arylmaleimides under various conditions.

Analysis of the spectral-luminescence properties of imidazo[1,2-b]pyrido[4,3-e][1,2,4]triazin-6(7Н)-ones.

The article presents a method for the construction of a new tricyclic system of imidazo[1,2-b]pyrido[4,3-e][1,2,4]triazin-6(7Н)-ones based on subsequent reactions of the obtained 1,2-diamino-4-phenylimidazole ethyl ether of 3-methyl-6-phenylimidazo[1,2-b][1,2,4]triazin-2-carboxylic acid with dimethylformamide dimethyl acetal and primary amines. The structures of the obtained compounds were confirmed using the data obtained from Н and С NMR, HRMS, and XRD analyses. We analyzed the dependence of the absorption and photoluminescence spectra on the structure of the compounds obtained using quantum chemistry methods.