The almost-two-centuries history of spectrochemical analysis has generated a body of literature so vast that it has become nearly intractable for experts, much less for those wishing to enter the field. Authoritative, focused reviews help to address this problem but become so granular that the overall directions of the field are lost. This broader perspective can be provided partially by general overviews but then the thinking, experimental details, theoretical underpinnings and instrumental innovations of the original work must be sacrificed.
View Article and Find Full Text PDFWe discuss the features involved in determining the titanium dioxide nanoparticle (TiONP) sizes in cosmetic samples via single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) in the millisecond-time resolution mode, and methods for considering the background signal. In the SP-ICP-MS determination of TiONPs in cosmetics, the background signal was recorded in each dwell time interval due to the signal of the Ti dissolved form in deionized water, and the background signal of the cosmetic matrix was compensated by dilution. A correction procedure for the frequency and intensity of the background signal is proposed, which differs from the known procedures due to its correction by the standard deviation above the background signal.
View Article and Find Full Text PDFIn this paper, we propose the combined procedure of noble metal (NM) determination, including fire assay, acid digestion, and reversible dynamic sorptive preconcentration, followed by flow-injection ICP-MS. Reversible preconcentration of all NMs was carried out using micro-column packed new PVBC-VP sorbent and elution with a mixture of thiourea, potassium thiocyanate, and HCl, which recovers Pd, Ir, Pt, and Au by 95% and Ru, and Rh by 90%. The proposed procedure was approved using certified reference materials.
View Article and Find Full Text PDFA scheme of determination of As, Bi, Hg, Sb, Se and Te with photochemical generation of their volatile derivatives and inductively coupled plasma mass spectrometry (ICP-MS) detection was developed. The volatile compounds were produced using a novel photochemical reactor with direct contact of a sample with an ultraviolet (UV) lamp. Essential experimental parameters such as the concentrations of the reagents and the flow rates of the carrier gas and the sample were optimized.
View Article and Find Full Text PDFA new algorithm for the estimation of the maximum temperature in a non-uniform hot zone by a sensor based on absorption spectrometry with a diode laser is developed. The algorithm is based on the fitting of the absorption spectrum with a test molecule in a non-uniform zone by linear combination of two single temperature spectra simulated using spectroscopic databases. The proposed algorithm allows one to better estimate the maximum temperature of a non-uniform zone and can be useful if only the maximum temperature rather than a precise temperature profile is of primary interest.
View Article and Find Full Text PDFA new algorithm for the evaluation of the integral line intensity for inferring the correct value for the temperature of a hot zone in the diagnostic of combustion by absorption spectroscopy with diode lasers is proposed. The algorithm is based not on the fitting of the baseline (BL) but on the expansion of the experimental and simulated spectra in a series of orthogonal polynomials, subtracting of the first three components of the expansion from both the experimental and simulated spectra, and fitting the spectra thus modified. The algorithm is tested in the numerical experiment by the simulation of the absorption spectra using a spectroscopic database, the addition of white noise, and the parabolic BL.
View Article and Find Full Text PDFA comparison of the efficiency of sorbents obtained by different methods of non-covalent immobilization of β-diketones on some low-polar matrices with respect to extraction of rare earth elements (REEs) was carried out. It was shown that sorbents containing reagent amounts of 1-8mmol/g can be obtained by sorption of reagents on low-polar matrices from aqueous and aqueous-organic solutions, and the value for the maximum capacity of the sorbent correlates with the specific surface of the matrix. Similar sorbents were also prepared by impregnating the matrix with reagent.
View Article and Find Full Text PDFJ Inorg Biochem
August 2014
Binding to plasma proteins is one of the major metabolic pathways of metallodrugs. In the case of platinum-based anticancer drugs, it is the interaction with serum albumin that affects most strongly their in vivo behavior. Since both the configuration, i.
View Article and Find Full Text PDFAnal Chim Acta
June 2013
The application of an inductively coupled plasma mass spectrometry (ICP-MS) assay for quantifying in vitro binding of a gallium-based anticancer drug, tris(8-quinolinolato)gallium(III), to serum albumin and transferrin and in human serum is described. The distribution of the drug between the protein-rich and protein-free fractions was assessed via ICP-MS measurement of total gallium in ultrafiltrates. Comparative kinetic studies revealed that the drug exhibits a different reactivity toward individual proteins.
View Article and Find Full Text PDFUrine analysis gives an insight into the excretion of the administered drug which is related to its reactivity and toxicity. In this work, the capability of inductively coupled plasma mass spectrometry (ICP-MS) to measure ultratrace metal levels was utilized for rapid assaying of gallium originating from the novel gallium anticancer drug, tris(8-quinolinolato)gallium(III) (GaQ(3)), in human urine. Sample dilution with 1% (v/v) HNO(3) as the only required pre-treatment was shown to prevent contamination of the sample introduction system and to reduce polyatomic interferences from sample components.
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