Publications by authors named "Mike Watts"

Article Synopsis
  • * Methods: A retrospective analysis was conducted on patients with Rutherford stages 4, 5, and 6, examining factors like lesion complexity and amputation rates while collaborating with a multidisciplinary team for complex cases.
  • * Results: The study involved 829 limbs, revealing a one-year mortality rate of 6.2%, major amputation rate of 2.3%, and a 78.7% success rate for clinically driven target lesion revascularization, indicating the efficacy of newer stent technologies in reducing the need for reinterventions.
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Background: The use of psychotropic medication is often the first line of treatment for people with mental distress. However, many service users discontinue their prescribed medication, and little is known about their experiences or the reasons why they choose to stop taking medication.

Aim: The aim of this review is to synthesize research literature focused on the experiences of people who decided to discontinue taking medication for their mental health problem.

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Many mental health service users decide to discontinue their psychotropic medication at some stage in the treatment process; however, few studies have captured these experiences. This study aimed to explore people's experiences of coming off medication. A qualitative descriptive design and individual interviews with 23 people who experienced coming off medication were employed.

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Article Synopsis
  • - The study focuses on 62 patients with poor graft function after receiving allogeneic hematopoietic stem cell transplants, who were treated with CD34+-selected stem cells from the same donor without pre-conditioning, resulting in 47 patients showing improvement and becoming independent from transfusions and growth factors.
  • - Key factors linked to recovery included having a shared seronegative status for CMV, being free from active infections, and matched sex between donor and recipient, with recovery rates being similar regardless of the level of donor chimerism.
  • - Five-year survival rates varied significantly among patients: 74.4% for those who fully recovered, 16.7% for partial recovery, and 22.2%
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Despite the continuous evolution of endovascular therapy, severe calcification remains a major issue for the minimally invasive treatment of superficial femoral artery (SFA) disease. The presence of calcium might negatively affect both the crossing of peripheral lesions and outcomes of all available treatment modalities and is therefore associated with unfavorable acute and long-term results. This manuscript summarizes the challenges raised from severe calcified atherosclerotic lesions and presents the outcomes of the various endovascular modalities in the treatment of calcified SFA disease.

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Plerixafor is a CXC chemokine receptor (CXCR4) antagonist that mobilizes stem cells in the peripheral blood. It is indicated (in combination with granulocyte-colony stimulating factor [G-CSF]) to enhance the harvest of adequate quantities of cluster differentiation (CD) 34+ cells for autologous transplantation in patients with lymphoma or multiple myeloma whose cells mobilize poorly. Strategies for use include delayed re-mobilization after a failed mobilization attempt with G-CSF, and rescue or pre-emptive mobilization in patients in whom mobilization with G-CSF is likely to fail.

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Unlabelled: Granulomatosis with polyangitiis (GPA) is a systemic small and medium vessel vasculitis, commonly associated with anti-neutrophil cytoplasmic antibodies (ANCAs). Presenting signs and symptoms in GPA are varied and patients may present with constitutional, non-specific symptoms, which can delay the diagnosis. Tissue biopsy of the site of active disease can confirm the diagnosis of GPA, in which necrotising granulomatous inflammation is seen.

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But is it science?

Early Child Dev Care

February 2017

Early years science education is not science, but a curricular construction designed to induct young children into a range of ideas and practices related to the natural world. While inquiry-based learning is an important approach to this, it is not of itself unique to science and there are a range of logico-mathematical constructions that come closer to the essence of science. In this paper we discuss just three: empirical question-asking, transgressive play, and good thinking.

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The provision of high-quality education and training that is responsive, relevant, accessible and evidence based is critical if the vision for quality mental health services presented in recent policy initiatives in Ireland is to be fulfilled. This paper reports the findings related to pedagogical approaches and quality assurance mechanisms utilized within mental health education. The study involved canvassing all Higher Education Institutions in Ireland.

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In recent years drug education has come under scrutiny. Research has found that drug education is having minimal impact. Questions have been raised as to the appropriateness of theories underpinning drug education programmes as well as the aims and purpose of programmes.

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Introduction: Closed head injury is associated with impairment in a range of executive skills, and with everyday difficulties in social interactions. Comprehension of pragmatic language plays an important role in social interactions. The present study was designed to examine performance on a task involving pragmatic judgement in people who had suffered closed head injury (CHI), and the relationship between this and any impairments in executive skills.

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