Epidemiologic features of invasive group A infection in a rural hospital: 6-year retrospective report and literature review.

Introduction: High rates of invasive group A disease were suspected by clinicians in northwestern Ontario. Patients with sepsis were being encountered with bacteremia positive for group A . This study was designed to assess the incidence of invasive group A Streptococcus infection in the region and provide best-practice treatment information.

Community-associated methicillin-resistant infection: Literature review and clinical update.

Objective: To provide information on the prevalence and treatment of methicillin-resistant (MRSA) infections and the distinction between community-associated MRSA and health care-associated MRSA.

Quality Of Evidence: The MEDLINE and EMBASE databases were searched from 2005 to 2016. Epidemiologic studies were summarized and the relevant treatment literature was based on level I evidence.

Evaluation of 6 remote First Nations community-based buprenorphine programs in northwestern Ontario: Retrospective study.

Objective: To evaluate established opioid addiction treatment programs that use traditional healing in combination with buprenorphine-naloxone maintenance treatment in 6 First Nations communities in the Sioux Lookout region of northwestern Ontario.

Design: Retrospective cohort study.

Setting: Six First Nations communities in northwestern Ontario.

Acute rheumatic fever in First Nations communities in northwestern Ontario: Social determinants of health "bite the heart".

Objective: To document a case series of 8 young First Nations patients diagnosed with acute rheumatic fever (ARF), a preventable disease that resulted in the death of 2 patients, in northwestern Ontario in the context of late diagnosis, overcrowded housing, and inadequate public health response.

Design: Retrospective case series over an 18-month period.

Setting: Remote First Nations communities in northwestern Ontario.

Community-wide measures of wellness in a remote First Nations community experiencing opioid dependence: evaluating outpatient buprenorphine-naloxone substitution therapy in the context of a First Nations healing program.

Objective: To document the development of unique opioid-dependence treatment in remote communities that combines First Nations healing strategies and substitution therapy with buprenorphine-naloxone.

Design: Quantitative measurements of community wellness and response to community-based opioid-dependence treatment.

Setting: Remote First Nations community in northwestern Ontario.

Invasive CA-MRSA in northwestern Ontario: a 2-year prospective study.

Introduction: Northwestern Ontario has a documented high rate of skin and soft-tissue infections due to community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). Recently, invasive illness from this common pathogen has become a serious clinical problem in the region. We sought to better understand this trend of invasive CA-MRSA.