Synthesis of fluorinated acid-functionalized, electron-rich nickel porphyrins.

In this study, novel fluorinated carboxylic acid esters of the generic structure TfO-CH-(CF) -COOCH ( = 2,4,6, Tf = triflate) were synthesized. The triflates were reacted with 2-hydroxy-3,4,5-trimethoxybenzaldehyde via Williamson ether syntheses. The resulting electron-rich compounds were used as aldehydes in the Rothemund reaction with pyrrole to form ester-substituted porphyrins.

Highly Sensitive, Easy-to-Use, One-Step Detection of Peroxide-, Nitrate- and Chlorate-Based Explosives with Electron-Rich Ni Porphyrins.

Homemade explosives, such as peroxides, nitrates, and chlorates, are increasingly abused by terrorists, criminals, and amateur chemists. The starting materials are easily accessible and instructions on how to make the explosives are described on the Internet. Safety considerations raise the need to detect these substances quickly and in low concentrations using simple methods.