Publications by authors named "Mikaelian R"

Neuronal reactivity to single stimuli applied to both the peripheral nerves and the cortex, was the same in the cat solitary tract nucleus. The 1-20 Hz stimulation frequency rendered the reactivity either tonic in character or with reduced firing rate. A high degree of convergence (80.

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Seventy eight patients with arterial hypertension were examined by echo-, radiocardiography and scintigraphy of the myocardium, using 99mTc pyrophosphate and 201Tl. A relationship was found between the development of hypertrophy of the left ventricle and the impairment of it perfusion and function. At the same time there was a correlation between the decrease in cardiac output and the deterioration of myocardial blood supply.

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In anesthetized cats, a high degree of reactivity (82.2%) of neurons was found to visceral nerves and visceral stimulation (single shocks and 2, 5, 10, 20 Hz) in the central nucleus of amygdala. The majority of the neurons revealed tonic changes of spontaneous activity.

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A study of 32 patients with arterial hypertension using echocardiography, electrocardiography and myocardial 99mTc-pyrophosphate scintigraphy, demonstrated that developing left-ventricular hypertrophy may interfere with myocardial perfusion. Regression of left-ventricular hypertrophy and recovery of myocardial perfusion is shown to be possible under the effect of antihypertensive treatment.

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The authors presented the results of a combined radionuclide study of the state of pulmonary hemodynamics in patients with essential hypertension. Altogether 132 patients were investigated. Radiocardiography, perfusion scintigraphy and a study of the regional pulmonary blood flow using radioactive Xe were conducted.

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Bipolar recording revealed EPs of maximal amplitude in stimulation of vagus, splanchnic and sciatic nerves in the region of amygdaloid corticomedial nuclei in anesthetized cats. A high degree of reactivity (68.3%) of neurons was found in this region to single-shock stimulation of the peripheral nerves.

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Proceeding from a study of the nature of changes in hemodynamics during development of hypertensive disease (HD) at its different stages it was shown that hemodynamic changes in 42.1% of the patients with Stage I-IIA HD were of hypertensive type, in the patients with Stage IIB-III HD normal and hypokinetic types of the blood circulation prevailed. After bicycle ergometry exercise the reactivity of the cardiovascular system was revealed more completely.

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The state of the cerebral blood flow in essential hypertension has been studied in relation to various clinical and hemodynamic parameters. The authors emphasize that the regulation of the cerebral blood flow depends to a great degree on the level of the systolic and pulse pressure as well as on the type of hemodynamics.

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The method of matrix isolation has been used to investigate mechanisms of gas-phase chemical reactions, in particular the pyrolysis of some organomercury compounds. A molecular beam of pyrolysis products was condensed simultaneously with a large excess of rare gas at temperatures from 5 to 15 degrees K to form a matrix that was subsequently studied by infrared spectroscopy. In the case of C(6)H(5)HgCCl(3), we found that pyrolysis in the temperature range 220-400 degrees C produced mainly dichlorocarbene.

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