Publications by authors named "Mikael Rabaeus"

Mediterranean diet is definitely one of the healthiest dietary models. Next questions are: is the traditional Mediterranean diet adapted to the modern environmental and existential conditions? Could and/or should it be "modernized" to adapt to the various geographical, environmental, ethnic, and religious characteristics? If "modernization" is required, which traditional Mediterranean foods should be imperatively conserved as they are? Alternatively, which "new" foods-not traditional or not Mediterranean-could be introduced to help people to still respect the basic healthy Mediterranean diet principles? The present article intends to help solving these new questions.

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Metabolic syndrome is considered as mainly caused by a deleterious lifestyle (sedentarity and diet). That smoking contributes to metabolic syndrome had been suggested by several small studies and a meta-analysis. The interesting study by Slagter et al.

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Early randomized controlled trials (RCTs) demonstrated the health benefits of omega-3 fatty acids (n-3), whereas recent RCTs were negative. We now address the issue, focusing on the temporal changes having occurred: most patients in recent RCTs are no longer n-3 deficient and the vast majority are now treated with statins. Recent RCTs testing n-3 against arrhythmias suggest that n-3 reduce the risk only in patients not taking a statin.

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Article Synopsis
  • Some doctors give cholesterol-lowering drugs to people with type 2 diabetes, but it's unclear if they actually help prevent heart problems.
  • A review found only four good studies on this, and most of them showed that these drugs didn't really lower the risk of dying or having heart issues in these patients.
  • The review suggests changing medical guidelines since it didn’t find enough proof that these drugs are helpful for people with type 2 diabetes.
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Article Synopsis
  • The JUPITER trial was a study that looked at a cholesterol-lowering drug and its effects on heart disease in people who didn't have heart issues and had normal or low cholesterol levels.
  • The trial was stopped early, and it showed some confusing results, like fewer strokes and heart attacks but no big change in how many people died from these issues.
  • The findings suggest using this drug to prevent heart disease might not be a good idea, and it raises questions about how commercial interests could affect research results.
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