Formulation and Evaluation of Triamcinolone Acetonide-Loaded Oral Disintegrated Film with Different Polymers Solvent Casting Method.

Objectives: The study aimed to investigate the effect of different polymers and plasticizers on oral disintegrating films (ODFs) containing triamcinolone acetonide (TA), a glucocorticosteroid indicated for the treatment of oral wounds.

Materials And Methods: Thirteen different formulations with the same amount of polymer and plasticizer were prepared by solvent casting. Briefly, the solutions containing polymer, plasticizer, and other ingredients were poured into Petri dishes and kept at room temperature for 20 hours to obtain ODFs.