Publications by authors named "Miho Obata"
Article Synopsis
- * The study examined 132 bats from 4 species in Yamaguchi Prefecture using PCR methods to detect various viruses.
- * Researchers identified herpesviruses, adenoviruses, astroviruses, and coronaviruses, finding 12 strains that are closely related to viruses from China and South Korea.
Background: Postoperative stricture and refractory stricture are severe adverse events which occur after expansive esophageal endoscopic submucosal dissection (ESD). The aim of this study was to assess the efficacy of steroid injection, polyglycolic acid (PGA) shielding, and of additional steroid injection thereafter for the prevention of refractory esophageal stricture.
Methods: This is a retrospective cohort study of 816 consecutive cases of esophageal ESD performed between 2002 and 2021 at the University of Tokyo Hospital.
Background: Sarcopenia prevalence has increased in proportion to the aging population in Japan. We aimed to investigate the association between sarcopenia and clinical outcomes and the prognostic factors of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC).
Methods: This retrospective study involved patients aged ≥ 65 years who had undergone gastric ESD for EGC at our institution between January 2009 and December 2019.
Article Synopsis
- Gastric adenocarcinoma of fundic-gland type (GA-FG) is a type of stomach cancer that is largely unaffected by Helicobacter pylori, but its molecular pathways are not well understood.
- A study involved analyzing gene expression in GA-FG tumors compared to normal tissue, revealing 1410 up-regulated and 1395 down-regulated genes, with NKX2-1/TTF-1 identified as a key transcription factor among the up-regulated genes.
- The findings indicate that NKX2-1/TTF-1 is overexpressed in GA-FG and retains its ability to regulate other genes involved in lung differentiation, suggesting its important role in the cancer's development.
Although the mortality rates of gastric cancer (GC) are gradually declining, gastric cancer is still the fourth leading cause of cancer-related death worldwide. This may be due to the high rate of patients who are diagnosed with GC at advanced stages. However, in countries such as Japan with endoscopic screening systems, more than half of GCs are discovered at an early stage, enabling endoscopic resection (ER).
View Article and Find Full Text PDFTexture and color enhancement imaging in magnifying endoscopic evaluation of colorectal adenomas.
World J Gastrointest Endosc
February 2022
Background: Olympus Corporation has developed texture and color enhancement imaging (TXI) as a novel image-enhancing endoscopic technique.
Aim: To investigate the effectiveness of TXI in identifying colorectal adenomas using magnifying observation.
Methods: Colorectal adenomas were observed by magnified endoscopy using white light imaging (WLI), TXI, narrow band imaging (NBI), and chromoendoscopy (CE).
Objectives: The natural history of sporadic non-ampullary duodenal epithelial tumors (SNADETs) is poorly documented. The aim of this study was to evaluate the history of SNADETs in patients where immediate resection could not be performed.
Methods: This is a single-center retrospective study of 86 consecutive cases of SNADETs who did not undergo immediate resection and were followed-up with upper gastrointestinal endoscopy for more than 6 months.
Background And Aim: Olympus Corporation released the texture and color enhancement imaging (TXI) technology as a novel image-enhancing endoscopic technique. We investigated the effectiveness of TXI in the imaging of serrated colorectal polyps, including sessile serrated lesions (SSLs).
Methods: Serrated colorectal polyps were observed using white light imaging (WLI), TXI, narrow-band imaging (NBI), and chromoendoscopy with and without magnification.
In this study, we investigated severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) infection in cats in Nagasaki, Japan. In total, 44 of 133 (33.1%) cats with suspected SFTS were confirmed to be infected with SFTSV.
View Article and Find Full Text PDFObjectives: Little has been reported on the yield and characteristics of colorectal neoplasia detected by the two-sample faecal immunochemical test (FIT), particularly the difference between subjects with two-positive results on the two-sample FIT and those with one-positive results. We aimed to assess risk stratification among patients with positive two-sample FIT to prioritise colonoscopy.
Design: A retrospective cross-sectional study.