Long-term efficacy of electroconvulsive therapy combined with different antipsychotic drugs in previously resistant schizophrenia.

Background: In treatment-resistant schizophrenia a combination of ECT with antipsychotics has been reported to have superior outcomes compared to other strategies, however the results were inconsistent. We investigated the long-term effects of the combination of unilateral, non-dominant hemisphere ECT with three antipsychotics.

Subjects And Methods: The clinical study was a naturalistic, prospective, open-labeled, active-controlled study in adult outpatients of both genders suffering from treatment-resistant schizophrenia with a follow up of 2 years.

Effectiveness of clozapine, haloperidol and chlorpromazine in schizophrenia during a five-year period.

Objective: The aim of our study was to evaluate the effects of low doses of clozapine in flexible regime in comparison with haloperidol and chlorpromazine in long term.

Method: The naturalistic study was prospective, active-controlled with 325 adult outpatients of both genders (140 females), with mean year age of 34.8 (range 21-57), suffering from chronic schizophrenia.

[Dr Mladen Jankovic - personality and work (1831-1885)].

Dr Mladen Janković was born in Kanjiza, in the district of Banat, in 1831. He completed the Hungarian High School in Segedin, and graduated from the Faculty of Medicine in Budapest, in 1856. Upon graduation, he moved to Serbia, where he was assigned to the position of a physician in the town of Krusevac.