Publications by authors named "Mihai Octavian Dan"
Background: The past decades have witnessed an increasing interest in the field of multimorbidity, as common risk factors such as obesity, arterial hypertension or diabetes have surged worldwide, thus posing a burden on public health systems all over the world. Defined as the presence of two or more conditions in the same individual, multimorbidity and its prevalence have shown large heterogeneity among countries and age groups. This cross-sectional study aimed to assess the presence of cardiovascular risk factors and multimorbidity in a cohort of 4200 patients of a Romanian private occupational medicine facility in order to provide a better outlook on this domain, adapted to patients in the active population group.
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- Gram-negative bacteria have significantly contributed to the rise of antimicrobial resistance, with many strains becoming multidrug-resistant (MDR) or extended-drug-resistant (XDR), making treatment increasingly difficult.
- New antibiotics like cefiderocol and ceftolozane/tazobactam have been approved and show promise in efficacy, yet bacteria are quickly adapting and developing resistance to these drugs.
- The review discusses the properties and resistance patterns of six new antibiotics, aiming to enhance understanding of bacterial resistance mechanisms and suggest future research directions.