Publications by authors named "Mihai Negutu"
Pain is a complex entity with deleterious effects on the entire organism. Poorly controlled postoperative pain impacts the patient outcome, being associated with increased morbidity, inadequate quality of life and functional recovery. In the current surgical environment with less invasive surgical procedures increasingly being used and a trend towards rapid discharge home after surgery, we need to continuously re-evaluate analgesic strategies.
View Article and Find Full Text PDFBackground: The sequential organ failure assessment (SOFA) score has poor discriminative ability for death in severely or critically ill patients with Coronavirus disease 2019 (COVID-19) requiring intensive care unit (ICU) admission. Our aim was to create a new score powered to predict 28-day mortality. Methods: Retrospective, observational, bicentric cohort study including 425 patients with COVID-19 pneumonia, acute respiratory failure and SOFA score ≥ 2 requiring ICU admission for ≥72 h.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates how changes in specific blood ratios (NLR, PLR, MLR, SII, dNLR) during the first 48 hours of ICU admission can predict the need for invasive mechanical ventilation (IMV) and death in critical COVID-19 patients.
- - Analyzing data from 272 severe COVID-19 patients, the findings show that a change in NLR of more than 2 significantly predicts IMV needs, followed by changes in SII and dNLR.
- - For mortality prediction, an NLR greater than 11 was found to be the strongest indicator, alongside dNLR over 6.93 and SII above 3700.