Publications by authors named "Mihaela Simona Naidin"
Background/objectives: The first reimbursed prescription for palbociclib (Palbo) in breast cancer patients in Romania was issued in July 2018. The objective of this study is to assess the efficacy, safety, and adherence to Palbo in combination with aromatase inhibitor (AI) or fulvestrant in a real-world cohort of HR+/HER2- breast cancer patients from Romania.
Methods: A retrospective analysis of reimbursed Palbo prescriptions was conducted using data extracted from the electronic database of the Romanian Health Insurance House, Dolj County, for disease code 124 (breast cancer), covering the period from 2018 to 2023.
Article Synopsis
- Glaucoma is a progressive eye condition linked to mitochondrial dysfunction that causes damage to retinal ganglion cells, and this review aims to explore the effect of daily niacin intake on this disease.
- Five relevant studies were analyzed, revealing that individuals with higher niacin consumption were less likely to have glaucoma compared to those with lower intake, suggesting a possible protective effect of niacin.
- However, due to variations in niacin intake, glaucoma definitions, and other influencing factors, further large-scale, controlled trials are necessary to definitively establish the benefits of niacin for glaucoma patients.
Background And Objectives: Previous studies have shown that the levodopa treatment of Parkinson's disease (PD) elevates circulating homocysteine levels, which are associated with an increased risk of cardiovascular and neurological disorders, or thrombosis. The present trial aimed to examine whether the intake of vitamin B12, folic acid, and vitamin D3 supplements improved homocysteine level and quality of life (QoL).
Materials And Methods: An interventional prospective trial was conducted in multiple centers across Romania.