Publications by authors named "Mihaela Sava"

Tuberculosis (TB) is a multisystemic contagious disease produced by complex bacteria (MTBC), with a prevalence of 65:100,000 inhabitants in Romania (six times higher than the European average). The diagnosis usually relies on the detection of MTBC in culture. Although this is a sensitive method of detection and remains the "gold standard", the results are obtained after several weeks.

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Article Synopsis
  • The study examines the efficacy of donated COVID-19 convalescent plasma (dCCP) in hospitalized adults with COVID-19 pneumonia, focusing on factors like antibody titers and patient characteristics.
  • The results showed that 85% of the dCCPs contained neutralizing antibodies, and while the transfusion didn't significantly affect survival rates, no adverse events were reported among dCCP recipients.
  • The findings highlight the variability in antibody responses among dCCP recipients, suggesting the need for controlled trials to utilize well-characterized dCCP with appropriate assays.
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Objectives: Patients with severe COVID-19 may be at risk of longer term sequelae. Long-term clinical, immunological, pulmonary and radiological outcomes of patients treated with anti-inflammatory drugs are lacking.

Methods: In this single-centre prospective cohort study, we assessed 90-day clinical, immunological, pulmonary and radiological outcomes of hospitalised patients with severe COVID-19 treated with tocilizumab from March 2020 to May 2020.

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Osteoporosis presents an increasing problem globally, primarily affecting older adults and postmenopausal women. Among important modifiable risk factors for osteoporosis, physical activity and calcium intake help reduce bone mineral loss and decrease the prevalence of osteoporosis. Although osteoporosis knowledge and health beliefs are associated with adopting preventive behavior and screening rates, few studies have evaluated them in Latin American populations.

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