Differential Biological Effects of Extracts-In Vitro Studies on Breast Cancer Models.

The increasing popularity of herbal supplements emphasizes the need of scientific data regarding their health benefits and possible toxicological concerns. The complexity of botanical extracts, which include thousands of distinct compounds, contributes to the challenging nature of this endeavor. In this study, we explored the hormetic effects of two extracts on breast cell lines.

Baseline pupil size encodes task-related information and modulates the task-evoked response in a speech-in-noise task.

Pupillometry data are commonly reported relative to a baseline value recorded in a controlled pre-task condition. In this study, the influence of the experimental design and the preparatory processing related to task difficulty on the baseline pupil size was investigated during a speech intelligibility in noise paradigm. Furthermore, the relationship between the baseline pupil size and the temporal dynamics of the pupil response was assessed.

Reclaim and Valorization of Sea Buckthorn () By-Product: Antioxidant Activity and Chemical Characterization.

The by-product resulting from the production of the sea-buckthorn () juice may be a functional food ingredient, being a valuable source of bioactive compounds, such as polyphenols, flavonoids, minerals, and fatty acids. For checking this hypothesis, two extracts were obtained by two different methods using 50% ethyl alcohol solvent, namely through maceration-recirculation (E-SBM) and through ultrasound extraction (E-SBUS), followed by concentration. Next, sea-buckthorn waste (SB sample), extracts (E-SBM and E-SBUS samples) and the residues obtained from the extractions (R-SBM and R-SBUS samples) were characterized for the total polyphenols, flavonoid content, antioxidant capacity, mineral contents, and fatty acids profile.

Dietary Phytoestrogens and Their Metabolites as Epigenetic Modulators with Impact on Human Health.

The impact of dietary phytoestrogens on human health has been a topic of continuous debate since their discovery. Nowadays, based on their presumptive beneficial effects, the amount of phytoestrogens consumed in the daily diet has increased considerably worldwide. Thus, there is a growing need for scientific data regarding their mode of action in the human body.

assessment of the cytotoxicity and anti-inflammatory properties of a novel dietary supplement.

Studies on the immunopharmacological activities of various plant species have provided evidence for the high therapeutic potential of different extracts. These represent a promising alternative to reduce the inflammatory processes and, thus, diseases related to inflammation. Numerous scientific studies strongly suggest that diet plays an essential role in inflammation, and that certain dietary factors can act as preventive or treatment methods to lower inflammation.